Abstract: Objective To investigate the risk factors and nursing strategies of hypertensive cerebral hemorrhage (HICH) complicated with upper gastrointestinal bleeding. Methods Two hundred and fourteen HICH patients admitted in our hospital from April, 2016 to September, 2017 were selected. Eighty-six HICH patients with upper gastrointestinal bleeding were set in observation group and 128 HICH patients without upper gastrointestinal bleeding were set as control group. The gender, age, hernia, pathological signs, cerebral hemorrhage sites, blood glucose level, cerebral hemorrhage, GCS score of two groups were accounted, and those risk factors of HICH patients with upper gastrointestinal bleeding was analyzed with univariate and multivariate analysis. Results In 214 HICH patients, 86 patients developed upper gastrointestinal bleeding with a rate of 40.2% (86/214). Univariate analysis showed that:age, hernia, pathological signs, cerebral hemorrhage site, blood glucose levels, cerebral hemorrhage, GCS score were the risk factor for HICH patients with upper gastrointestinal bleeding. Multivariate logistic regression analysis showed that age, hernia, pathological signs, cerebral hemorrhage site, blood glucose levels, cerebral hemorrhage, GCS score were the risk factor for HICH patients with upper gastrointestinal bleeding. Conclusion Hypertensive intracerebral hemorrhage patients easily upper gastrointestinal bleeding, and age, hernia, pathological signs, cerebral hemorrhage site, blood glucose levels, cerebral hemorrhage, GCS score were the risk factors for HICH patients with upper gastrointestinal bleeding. So those risk factors should be pay attention,and treatment and nursing carried out to prevent the occurrence of upper gastrointestinal bleeding.