Abstract: Objective To investigate the effects of time theory based rehabilitation training on cardiac function and quality of life in patients with unstable angina pectoris. Methods A total of 100 patients with unstable angina pectoristreated in our cardiology department were selected as subjects from March, 2015 to February, 2017. They were divided into training group (50 cases) and control group (50 cases) according to the random number table method. The control group was given routine nursing method, the training group gave the time theory based rehabilitation training. left ventricular ejection fraction (LVEF), 6 min walking distance (6 MWD), New York Heart Association Functional Classification (NYHA), Seattle angina questionnaire (SAQ) score and 6 months of dysmenorrhea were compared between the two groups. Results The levels of LVEF and 6MWD in the two groups after 6 months discharge were significantly higher than those before the intervention (all P<0.05). The NYHA classification in two groups 6 months after discharge was significantly lower than that before intervention (P<0.05). The levels of LVEF and 6MWD in the training group 6 months after discharge were significantly higher than those in the control group (all P<0.05). The NYHA classification in the training group 6 months after discharge was significantly lower than the control group (all P<0.05). The score of frequency of angina pectoris in the control group 6 months after discharge was significantly higher than that before the intervention (P<0.05). All quality of life scores in the training group 6 months after discharge were significantly higher than those before the intervention (all P<0.05). The quality of life scores in the training group were significantly higher than those in the control group 6 months after discharge (all P<0.05). The incidence of adverse events in the training group was significantly lower than that in the control group (all P<0.05). Conclusion The time theory based rehabilitation training can effectively improve the cardiac function and quality of life of patients with unstable angina pectoris, which is worthy of clinical application.