Abstract: Objective To explore the effect of single eye vein drainage and multiple venous drainage on proptosis, conjunctival congestion, edema, limited eyeball movement, diplopia, impaired vision in patients with traumatic carotid-cavernous fistulas (TCCF). Methods Total 93 cases of TCCF were divided into single venous drainage group and multiple venous drainage group. The distribution of ophthalmic symptoms, such as proptosis, conjunctival congestion, edema, limited eyeball movement, diplopia, impaired vision and the outcome were compared between the two groups. Results The symptoms of proptosis, conjunctival congestion, edema, diplopia, impaired vision of these two groups had no difference (P>0.05). But there were 15 cases of limited eyeball movement in multiple venous drainage after the treatment, and there was a significant difference in these two groups (P<0.05). Conclusion Different venous drainage for TCCF can make difference in eyeball movement. The recovery of ocular symptoms (especially limited eyeball movement) of TCCF patients has relationship with the improvement of abnormal blood flow within the cavernous sinus, also with vein expansion and deep vein drainage during multiple venous drainage procedure. So we should choose suitable venous drainage in the treatment.