Abstract: Objective To investigate the clinical effect of the second stage of labor stages by free delivery position. Methods One hundred and twenty cases of primipara accepted natural childbirth were selected according to the order of admission were randomly divided into observation group (n=60) and control group (n=60), the observation group at the beginning of the second stage of labor by standing, half sitting, squatting three vertical position childbirth, maternal according to their own subjective hope free alternative selection adjustment delivery the position of the second stage of labor; at the end of the fetal head exposed after taking lateral position shifting production; the control group in the second stage of labor throughout the supine lithotomy position delivery. The birth outcomes, length of the second stage of labor, postpartum hemorrhage and neonatal asphyxia rate 2 h, perineal laceration, comfort and satisfaction of delivery in the two groups were compared. Results In the observation group, the vaginal delivery rate was higher than the control group, the difference was statistically significant (P<0.05). The neonatal asphyxia, postpartum hemorrhage 2 h comparison in the two groups had no statistically significant difference (P>0.05). The second stage of labor time length in the observation group was lower than the control group, the difference was statistically significant (P<0.05). The perinaeum integrity and episiotomy rate in the observation group were better than the control group, the difference was statistically significant (P<0.05). The maternal comfort and satisfaction in the observation group were higher than the control group, the differences were statistically significant (P<0.05). Conclusion The second stage of labor stage free position childbirth way of birth is safe and effective. It can improve the rate of natural childbirth, shorten the second stage of labor, reduce perineal injury, improve maternal comfort and have good effects on maternal and neonatal outcomes are, with clinical application.