Abstract:
Objective Immediate cord clamping (ICC) is a routine clinical practice after delivery of the fetus, however, delayed cord clamping (DCC) can make the fetal blood in placenta flow back sufficiently to collect more flood, and has positive effects on the prevention of neonatal anemia. No study has confirmed the risk of DCC on neonatal jaundice. The aim of this study is to explore the effects of DCC on neonatal jaundice in full term vaginal delivery neonates through comparing ICC and DCC.
Methods A total of 1 867 cases with full term vaginal delivery were selected in the second hospital affiliated to Wenzhou city in Zhejiang province July, 2017 to September, 2017, they were divided into observation group and control group randomly. Nine hundred infants in observation group received delayed cord clamping and 967 infants in control group received routine cord clamping. Umbilical cord of infants in the observation group was clamped from 30 s to 180 s after delivery, then umbilical cord in the control group was clamped in 30 s after delivery. They were monitored and compared in two groups that the level of neonatal daily transcutaneous bilirubin, the incidence of neonatal jaundice, the incidence of high blood bilirubin, bilirubin encephalopathy incidence index.
Results The level of neonatal daily transcutaneous bilirubin in 1-5 day were examined, they were (3.43±0.76), (7.15±0.85), (11.23±0.74), (12.37±1.04) and (13.68±1.49) mg/dl in observation group and which were (3.12±0.43), (7.07±0.74), (11.11±0.68), (12.01±1.13) and (12.96±1.58) mg/dl. The level of neonatal daily transcutaneous bilirubin in observation group was higher than that in control group, but no significant difference was found between the two groups (
P>0.05). There were the same results in the incidence of neonatal jaundice, the incidence of high blood bilirubin and blue light treatment. And there were no bilirubin encephalopathy in the two groups.
Conclusion Delayed cord clamping has no significant effect on neonatal jaundice, and does not increase incidence of neonatal jaundice, It is safety and feasible, deserve the clinical expansion.