Abstract: Objective To explore the effects of cluster intervention of TCM on blood pressure of the climacteric syndrome patients with stagnation of liver-QI and hypertension, in order to provide easy, safe and reliable treatment scheme, alleviate clinical symptoms of traditional Chinese medicine, and improve the quality of life. Methods A total of 80 hypertension patients with climacteric syndrome were randomly divided into control group and experimental group with 40 patients in each group. The control group was given routine nursing care while the experimental group was given the cluster TCM interventions. The differences in 24 h SBP, 24h DBP and TCM symptom classifying quantitative score were compared between the two groups after treatment. Results The experimental group's 24 hours average systolic blood pressure (SBP) reduced from (155.8±5.1) mm Hg (1 mm Hg=0.133 kPa) to (123.5±3.3) mm Hg, 24 hours a day on average diastolic blood pressure(DBP) reduced from (93.6±6.9) mm Hg to (70.8±3.6) mm Hg, TCM symptom classifying quantitative score from (8.2±1.3) to (1.4±0.5); Control group' SBP reduced from (155.9±5.1) to (128.2±4.4), DBP by (95.3±5.2) mm Hg to (76.4±3.7) mm Hg, TCM symptom classifying quantitative score by (9.4±1.5) to (3.7±1.1). Comparison between groups, after twenty days intervention, experimental group' SBP and DBP drop was obvious; after ten days intervention, experimental group' TCM symptom also decreased significantly. Conclusion According to the theory of Chinese medicine keeping in good health cluster change intervention can improve the menopausal liver Yang syndrome blood pressure in patients with high blood pressure, relieve clinical symptoms of traditional Chinese medicine, and improve the quality of life.