Abstract: Objective To investigate the clinical efficacy on the treatment of Daozhi Tongbian manipulation for treating children constipation with excess syndrome. Methods Random number method was used to divide 120 cases of constipation in our hospital from December, 2015 to December, 2017 into two groups, 60 cases in each group. The control group was treated with Medilac-Vita medicine and the observation group was treated with Daozhi Tongbian manipulation. Comparing the scores of TCM syndromes before and after treatment in the two groups (defecation difficulty, stool quality, defecation interval, abdominal distention and abdominal pain, refraining from feeding, feverish palms and soles, sleep disturbance, upset, short yellow urine and thick red tongue coating). Clinical efficacy and incidence of adverse reaction during treatment. The effect of guiding Daozhi Tongbian manipulation on children constipation with excess syndrome was analyzed, through the analysis of prognostic data of two groups. Results After treatment, the total scores of TCM symptoms in the two groups decreased significantly (P<0.05), and the observation group was significantly lower than the control group (P<0.05). After treatment,the degree of difficulty in defecation, the quality of constipation,and the time between defecations were significantly decreased in both groups (P<0.05), and the observation group was significantly lower than the control group (P<0.05). After treatment, abdominal distention and abdominal pain in the groups, refraining from feeding, feverish palms and soles, sleep disturbance, upset, short yellow urine and thick red tongue coating were significantly lower (P<0.05), and the observation group was significantly lower than the control group (P<0.05). After treatment,the total effective rate of the observation group was 96.67%, which was significantly higher than that of the control group (71.67%, P<0.05). No obvious adverse reaction were seen during the treatment of both groups. Conclusion Compared with oral drug therapy, Daozhi Tongbian manipulation can significantly improve the clinical symptoms of children constipation with excess syndrome.