Abstract: Objective As the demand for medical care continues to grow, quality medical resources cannot fully meet the growing needs of the general public. How to provide convenience for patients and save patient's waiting time to improve outpatient work efficiency is the most concerned issue for patients and is a common problem faced by large public hospitals. Methods Based on the background of ‘Internet+’, this article explores the daily consultation time by half hour as a unit according to the time-based full appointment medical treatment. According to the characteristics of different departments, the number of theoretical consultations per unit time is set to the patient's visit time which can be specific to the minute, and through the provision of an appointment registration, the patient can know the time of his/her visit when making an appointment, understand the registration expert's clinic time, reduce the concentration and detention of the patient, and further protect the patient's medical safety as well as to achieve the diversion of the visiting population and improve the medical environment. Results In the southern part of our hospital, the current situation of supply and demand of hospital outpatient clinics, after the appointment registration, based on the summary of this experience, we proposed a time-based full appointment registration system, which through the nearly half a year of exploration and practice, achieved good results. The system can effectively improve the appointment rate of outpatients, optimize the time distribution of outpatients, and effectively facilitate patients to seek medical treatment. Conclusion The implementation of the multi-channel model with full-schedule appointments has effectively changed the patient's registration habits and improved the appointment rate. At the same time, it has also improved the medical environment and rationalized the allocation of medical resources, which is conducive to the long-term development of the hospital.