Abstract: Objective To analyze the sleep quality of adults with sleep disorders in a single center from 2013 to 2017, so as to understand their continuous dynamic changes. Methods Adult sleep disorder patients who visited the hospital from 2013 to 2017 were studied, the sleep quality was assessed with the Pittsburgh sleep quality index (PSQI), and the data were statistically analyzed via SPSS 21.0. Results A total of 2 112 patients with sleep disorders were diagnosed from January, 2013 to December, 2017. The ratio of male to female was about 0.81:1, age ranging from 20 to 39 accounting for the most. In general, the score of the partial PSQI questionnaire and the total score of PSQI was increased yearly. Comparison between men and women, the total score of PSQI about women in 2013, 2014 and 2017 was higher. The PSQI scores of >60 years old group were the highest among different age groups. Conclusion The number of cases of sleep disorders in adults increased year by year from 2013 to 2017, with 20-39 years old as the main group of patients with sleep disorders. From 2013 to 2017, the sleep quality of the patients with sleep disorders was generally declining. The sleep quality of women >60 years old group had worse sleep quality. The object is from a single center, the representativeness of samples is limited, and the evaluation index is limited. There is still a big gap in the study of quality of sleep. In the future investigation, more factors should be considered and verified and explored in a larger sample population.