Abstract: Objective To analyze the influence factors of neurologic complications associated with endovascular treatment (EVT) in patients with rupture intracranial aneurysms (RIAs) and provide a reference for the clinical treatment of EVT in RIAs patients. Methods A total of 75 cases of RIAs meeting the inclusion criteria in our hospital from Mach 2012 to January 2017 were enrolled into this study. The patients were treated with EVT and followed up for 6 months. According to the neurologic complications after EVT therapy, the patients with EVT associated neurological complications were included in the complication group (n=24), and the patients without the associated complications were included in the uncomplicated group (n=51). The general data (gender, age, hypertension, diabetes, cerebral infarction history, HuntHess classification and CT Fisher classification, etc), aneurysms related indicators (the number of aneurysms, the maximum diameter, position, shape, tumor cyst and aortic arch typing. etc) and EVT treatment (surgical procedures, surgical methods, rupture to embolization time, embolization effect and blood sodium level) were compared between the two groups. The binary logistic was performed to analyze the influence factors of neurologic complications associated with EVT in RIAs patients. Results The hypertension, Hunt-Hess classification, Fisher classification, tumor cyst, wide-necked aneurysm, surgical methods and blood sodium level in uncomplicated group were significantly differences with the complication group (P < 0.05). The main influence factors of neurologic complications in RIAs associated with EVT were the Hunt-Hess classification, surgical methods, tumor cyst and wide-necked aneurysm. Conclusion The Hunt-Hess classification, surgical methods, tumor cyst and wide-necked aneurysm are the influence factors of neurologic complications associated with EVT in RIAs patients.