Quality of life, anxiety and depression in facial dermatitis patients with pruritus
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摘要: 目的 了解面部皮炎患者抑郁、焦虑情绪及生活质量情况,并分析其相关影响因素。 方法 选取2015年3月-2017年1月北京大学第三医院收治的85例面部皮炎患者进行皮疹严重度评分和瘙痒程度评分(VAS),并采用皮肤病生活质量指数(DLQI)和医院焦虑抑郁量表(HADS)进行评估,对评估结果及相关因素使用SPSS 23.0统计软件进行统计学分析。 结果 病例组焦虑及抑郁水平较健康对照组明显升高(HAD-A评分5.14±3.12,焦虑阳性者21.3%;HAD-D评分3.76±3.06,抑郁阳性者12.5%;焦虑和抑郁并存者8.8%),生活质量明显受损(DLQI评分8.89±6.03)。面部皮炎患者的年龄、性别和病程长短对其生活质量和焦虑、抑郁情绪均无相关性;皮疹严重度与焦虑、抑郁水平均无明显相关性(均P>0.05),与生活质量呈正相关(r=0.261,P<0.05);瘙痒程度(VAS)与焦虑情绪呈正相关性(r=0.403,P<0.01),与抑郁情绪无明显相关性(P>0.05),与生活质量呈正相关(r=0.513,P<0.01)。多重回归分析显示,瘙痒是影响面部皮炎患者焦虑情绪和生活质量的独立因素。 结论 面部皮炎患者生活质量明显受损,较正常人群焦虑及抑郁水平升高。患者的客观皮疹症状越重,生活质量越差,但与抑郁、焦虑情绪相关性均不明显。主观瘙痒程度越重,生活质量越差,焦虑症状也越重。提示临床工作中不仅要治疗疾病,也要重视患者心理需求,尝试多学科联合治疗。Abstract: Objective To evaluate the quality-of-life, anxiety and depression in patients with facial dermatitis, and to analyze the possible impact factors. Methods Totally 85 patients with facial dermatitis were recruited. They were assessed with erythra severity score, Visual Analogue Sale (VAS), Dermatology Life Quality Index (DLQI) and Hospital Anxiety and Depression Scale (HADS), while outcomes and related factors were analyzed by SPSS 23.0. Results The patients with facial dermatitis scored higher in HADS than the healthy controls (P<0.05), the mean scores of "anxiety" and "depression" were HAD-A 5.14±3.12 and HAD-D 3.76±3.06 respectively, 21.3% were anxious, 12.5% were depressed, and 8.8% were both anxious and depressed. Quality of life was impaired obviously (DLQI scored 8.89±6.03). The age, gender, and course of disease have no correlation with quality of life, anxiety or depression level. Erythra severity scores were negatively correlated with Quality of life (r=0.261, P<0.05), meanwhile they showed no correlation with anxiety and depression level (P>0.05). The degree of itch (VAS) was positively correlated with anxiety level (r=0.403, P<0.01), negatively correlated with Quality of life (r=0.513, P<0.01), and it showed no correlation with depression level. Multivariable regression showed that pruritus was an independent impact factor of anxiety and quality-of-life in patients with facial dermatitis. Conclusion The patients with facial dermatitis had higher levels of anxiety and depression compared with healthy controls, and lower quality of life. Quality of life was negatively affected with both subjective and objective symptoms severity. Anxiety level was only negatively affected with Subjective severity (degree of itch). The more severe itching, the worse the quality of life, and the higher the anxiety level. Not only disease but also patients' psychological needs should be paid attention in clinical work, and multidisciplinary treatment should be tried.
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Key words:
- Facial dermatitis /
- Pruritus /
- Depression /
- Anxiety /
- Quality of life
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