Abstract: Objective To explore the application effect of crisis management mode combined with traditional trauma emergency care on patients with emergency craniocerebral injury. Methods Ninety patients with emergency craniocerebral trauma admitted from February 2017 to September 2018 were randomly divided into observation group and control group, with 45 cases in each group. The patients in the control group were treated with traditional trauma emergency care, and the patients in the observation group were combined with the crisis management model based on the control group. Complication rate, incidence of adverse events during nursing, neurological function (stroke scale, NIHSS score) and coma degree (Glasgow coma index, GCS score) were compared between the two groups. Results There were no serious complications (cerebral hernia) in both groups. The total incidence of complications including limb dysfunction, swallowing dysfunction, pulmonary infection and electrolyte disturbance in the observation group was 4.4%(2/45), which was lower than that in the control group (17.8%, 8/45), P<0.05. The incidence of crisis events in the observation group was 8.9% lower than that in the control group (24.4%, P<0.05); there was no significant difference in NIHSS score and GCS score between the two groups before nursing intervention (P>0.05). After nursing, the NIHSS score of the patients in the observation group was significantly lower than that of the control group, and the GCS score of the patients in the observation group was higher than that of the control group(P<0.05). Conclusion Crisis management mode combined with traditional trauma first aid nursing is conducive to improving the first aid efficiency of emergency patients with craniocerebral injury, reducing the occurrence of complications, and improving patients' nervous function, and reducing the incidence of adverse events during nursing, which is worthy of clinical application.