Abstract: Objective To study the effect of risk nursing in obstetrics and its effect on postpartum infection. Methods A total of 90 pregnant women who were admitted to the department of obstetrics and gynecology of our hospital from March 2015 to March 2016 were selected. According to the method of random numbers, they were divided into routine nursing group and risk nursing group, with 45 cases in each group. The routine nursing group adopted the routine nursing method, and the risk nursing group adopted the risk prevention method for nursing. Anxiety self-rating scale (SAS) and depression self-rating scale (SDS) were used to evaluate the psychological status of parturients, and nursing satisfaction was investigated to calculate the hospitalization time, medical error rate and postpartum infection of the two groups. Results The SAS and SDS scores of the conventional nursing group and the risky nursing group were significantly lower than those before nursing, showing statistical difference (P<0.05). After nursing, the SAS and SDS scores of the risky nursing group were lower than those of the conventional nursing group, showing a statistical difference (P<0.05). The hospitalization time of the routine nursing group was higher than that of the risk nursing group, showing statistical difference (P<0.05). The rate of medical error in the conventional nursing group was higher than that in the risk nursing group, showing statistical difference (P<0.05). The total nursing satisfaction of the risky nursing group was significantly higher than that of the conventional nursing group, showing a statistical difference (P<0.05). The total infection rate of parturients in the risky nursing group was lower than that in the conventional nursing group, showing a statistical difference (P<0.05). Conclusion The effect of risk nursing in obstetric application is remarkable. It can reduce the occurrence of maternal depression, shorten the hospital stay and reduce the incidence of postpartum infection.