Abstract: Objective To explore the effect of integrated nursing mode on gastric polyposis patients undergoing endoscopic mucosal resection. Methods A total of 120 patients with gastric polyps admitted to the Affiliated Hospital of Shaoxing University of Arts and Sciences from January 2017 to January 2019 were selected. All patients underwent endoscopic mucosal resection. They were divided into observation group (60 cases) and control group (60 cases) according to random number table method. Patients in the observation group were given integrated medical and nursing care, while patients in the control group were given routine nursing care. The post-operative recovery of the two groups was compared, and the psychological state scores of the 2 groups before and after nursing intervention were compared according to the State Trait Anxiety Scale. The incidence of complications and nursing satisfaction of the two groups were counted. Results The recovery time of bowel sounds, the first exhaust time, the first defecation time and the hospitalization time of the patients in the observation group were shorter than those in the control group (all P<0.05); before nursing intervention, there was no significant difference in the scores of state trait anxiety scale between the two groups (all P>0.05); after nursing intervention, the scores of the patients in the observation group were lower than those in the control group (all P<0.05); the incidence of complications in the observation group was 3.3% (2/60) lower than that in the control group 13.3% (8/60), P<0.05; the scores of nursing satisfaction in the observation group (timeliness, suitability, continuity and comprehensiveness were higher than those in the control group (all P<0.05). Conclusion Compared with routine nursing, the integrated nursing mode can promote the recovery of gastric polyp patients after endoscopic mucosal resection, reduce hospitalization time, reduce anxiety, reduce the occurrence of postoperative complications and improve nursing satisfaction, which is worthy of clinical application.