Abstract: Objective To investigate the effects of different vitamin A and E levels on pregnancy outcome in pregnant women with preeclampsia. Methods One hundred and twenty cases of preeclampsia pregnant women admitted to our hospital from March 2017 to March 2018 in Ukrainian Maternal and Child Health Hospital Obstetrics and Gynecology were selected as experimental subjects. The serum vitamin A and E levels were determined according to their 12-20 weeks. Vitamin A and E were normal. 30 patients in the group (control group), 30 patients with normal vitamin/E deficiency (observation group a), 30 patients with vitamin A deficiency/E normal group (observed group b), and 30 patients with abnormal vitamin A and E (observation group), comparing the preterm birth rate, induction rate, stillbirth and neonatal asphyxia in 4 groups of pregnant women. Results The preterm birth rate of the observation group was higher than that of the other 3 groups. The induction/abortion rate was slightly higher than that of the observation group a, the observation group b and the control group (all P>0.05). The neonatal asphyxia rate in the observation group was significantly higher than that in the other 3 groups. The significance of learning (all P<0.05); 6 cases (20.00%) of postpartum hemorrhage in the control group, 11 cases (36.67%) in group a, 13 cases (43.33%) in group b, and 17 cases (56.67%) in observation group, observed The bleeding volume of the patients in the group was higher than that in the other 3 groups. The average blood loss of the group a and the b group was not significantly different from that of the control group. The neonatal Apgar score control group was higher than the other 3 groups. Conclusion Serum vitamin A and E levels in patients with preeclampsia have a greater impact on pregnancy outcomes. Pregnant women with normal vitamin levels have higher maternal and child safety.