Intervention effect of new pharmaceutical care model on drug safety and compliance of patients
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摘要: 目的 考察施行新型药学服务模式对患者用药的影响。 方法 2018年6—8月在绍兴市立医院门诊共纳入200例需要用药治疗的患者进行临床观察。年龄18~75岁,男女不限。将全部患者按随机数字表法分为传统模式组和新型模式组,每组100例,2组的年龄、性别比例、文化程度等基线资料比较差异均无统计学意义(均P>0.05),具有可比性。传统模式组:应用传统药学服务模式为患者施行临床药学服务,主要是根据医生的处方内容进行配药、发药,审核特殊处方,指导患者谨遵医嘱或按照药品说明书正确用药,为咨询患者提供用药指导,及对门诊特殊患者进行药学监护。新型模式组:应用新型药学服务模式施行临床药学服务,主要工作内容是在配药、发药等传统药学服务内容之外,还要求临床药师为患者提供临床用药咨询等药学服务。比较2组患者的用药依从率,药品差错事件发生率,药物不良反应发生率。 结果 新型模式组患者的用药依从率为100.0%,显著高于传统模式组的92.0%(χ2=11.020,P=0.001)。新型模式组的药品差错事件发生率为2.0%,显著低于传统模式组的9.0%(χ2=8.320,P=0.004)。新型模式组(11.0%)和传统模式组(28.0%)药物不良反应发生率比较,差异无统计学意义(χ2=0.090,P=0.762)。 结论 施行新型药学服务模式可以提高患者的用药依从性,较少药品差错事件发生率,在临床具有积极的推广意义。Abstract: Objective To investigate the effect of the implementation of new pharmaceutical care model on drug use in patients. Methods From June to August 2018, 200 patients in Shaoxing Municipal Hospital were enrolled for clinical observation. Ages ranged from 18 to 75. Men and women were not limited. All patients were divided into Traditional Model Group and New Model Group according to random number table method. There were 100 cases in each group. There was no statistical difference in baseline data such as age, sex ratio and education level between the two groups (P>0.05). For the Traditional Model Group, clinical pharmaceutical care for patients is mainly based on the prescription content of doctors, dispensing drugs, auditing special prescriptions, guiding patients to follow doctor's instructions or use drugs correctly according to drug instructions, providing drug guidance for consulting patients, and carrying out pharmaceutical care for special patients in outpatient clinics. For the New Model Group, applying new pharmaceutical care mode to carry out clinical pharmaceutical care, the main content of which is not only traditional pharmaceutical care, such as dispensing drugs, dispensing drugs, but also requiring clinical drug noise to provide patients with clinical drug counseling and other pharmaceutical care. Comparison was made regarding to the drug compliance rate, the incidence of drug errors and adverse drug reactions between the two groups. Results The compliance rate of the observation group was 100.0%,which was significantly higher than that of the control group (92.0%, χ2=11.020,P=0.001). The incidence of drug errors in the observation group (2.0%) was significantly lower than that in the control group (9.0%, χ2=8.320, P=0.004). There was no significant difference in the incidence of adverse drug reactions between the observation group (11.0%) and the control group (28.0%, χ2=0.090, P=0.762). Conclusion The implementation of the new pharmaceutical care model can improve the drug compliance of patients and reduce the incidence of drug errors. It has a positive significance in clinical practice.
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Key words:
- Pharmaceutical care model /
- Drug therapy /
- Compliance /
- Adverse drug reactions
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