Abstract: Objective To explore the predictive value of coronary calcification score for cardiovascular event risk in dialysis patients. Methods From January 2016 to June 2017, 148 patients receiving MHD treatment in our hospital were selected and divided into observation group and control group according to whether cardiovascular events occurred during the observation period (18 months). General data, vital signs, blood biochemical examination, coronary calcification score, Framingham risk score and EuroSCORE Ⅱ score were compared between the two groups. ROC curves were used to evaluate the predictive efficacy of different models in predicting cardiovascular events. Results Sixty-one cases (41.22%) of cardiovascular events occurred in this study. There were significant differences in total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, high-density troponin, b-type natriuretic peptide and Glomerular Filtration Rate (GFR) between the two groups (all P<0.05). The coronary artery calcification score of observation group was significantly higher than control group (t=7.714, P<0.001). There were significant difference in Framingham risk score and the EuroSCORE Ⅱ score between the two groups (Z=6.288, 5.003; all P<0.001). The AUC of coronary artery calcification score, Framingham risk score and EuroSCORE Ⅱ score was 0.903, 0.768 and 0.740, respectively. The arterial calcification score was significantly better than others (Z=2.917, 3.428; P=0.003, <0.001), and the sensitivity of arterial calcification score prediction was 90.16%, which was significantly better than Framingham risk score and EuroSCORE Ⅱ score (all P<0.05). Conclusion Coronary calcification score is a good predictive value for the occurrence of cardiovascular events in dialysis patients, it is worthy of further study and discussion.