Abstract: Objective To evaluate the effect of the procedural pain nursing management during total hip arthroplasty. Methods From October 2016 to May 2019, 80 patients from the first people's hospital of Chuzhou who required hip replacement were chosen. The patients were divided into control group and observation group according to random number table. Each group had 40 patients. The control group adopted routine nursing measures and analgesic treatment, while the observation group set up a programmed pain management group and were given patients pain knowledge education and multi-mode analgesic measures. Patients' daily living activity score(ADL), hip joint function score scale and pain score were evaluated before operation, 24 and 48 hours after operation. Results The programmed pain nursing management had no effect on the daily living ability score of the patients 24 hours after the operation, but increased the daily living ability score of the patients 48 hours after the operation(49.78±6.51) and hip function scores(65.85±4.29). The postoperative pain degree of patients was reduced at 24 hours(3.82±1.13) and 48 hours(4.95±1.58). Conclusion The procedural pain nursing management can improve postoperative hip replacement patients daily life activities ability(48 hours after surgery) and hip function(48 hours after surgery), reduce postoperative pain reaction of patients(24 hours and 48 hours after surgery), and improve the patients' treatment adherence and psychological threshold, promote the patients' self-care ability to restore limb function in daily life, shorten the length of hospital stay, reduce the cost of treatment, and finally promote patients recovery of disease.