Abstract: In the developed countries of Europe and the United States, which have entered in aged stage earlier, there are mature and perfect systems and management models of formal and informal care mechanism after decades of operation in the classified treatment, classified diagnosis and treatment and social integration services for the elderly living in the community with multiple diseases. However, China's aging is relatively late, but progresses rapidly, accompanied by the ageing, empty nest and the weakening of traditional family care functions. The multiple diseases, the increasing proportion of disabilities and dementia, and the start of social services, a shortage of human resources in medical and nursing professional services and daily life care services have made the community home care for the elderly with multiple diseases become the root of self-anxiety and the important livelihood issues concerned by the government. It not only affects the quality of life of individuals, but also brings heavy care and economic burden to the family and society. Due to the different educational level, occupational experience, economic status and self-care ability of the elderly individuals with multiple diseases, there are great differences in the content, form and delivery of care services. How to provide individualized, targeted, appropriate health care and daily care services is a serious challenge for service providers, service organizations and government management. Drawing on the experiences and models of developed countries, we should rationally replicate and adaptably innovate the informal care services suitable for local culture, break through the bottleneck constraints of the shortage of personnel, management to be standardized and economic conditions in formal care. We should guide and promote the orderly and standardized development of informal care, and make up for the deficiencies of informal care undertaken by traditional families, to enhance their acquisition and happiness for the elderly with multiple disease living at home in community.