Abstract: Objective To analyzes the development trend of global research on intracranial atherosclerotic diseases based on the bibliometric method, analyzes the current situation and shortcomings of relevant research in China, and explores the appropriate coping strategies. Methods Relevant literatures of global research on intracranial atherosclerotic diseases from 1900 to 2018 in SCI expanded database were retrieved and quantitatively analyzed by the software of web of science, Excel 2007 and other software. The indicators included literature quantity, cited frequency, h-index, fund paper ratio, high contribution institutions, etc. Relevant literatures from China were separately analyzed and compared with those from the United States, Japan and Germany. Results There were 8 468 articles related to intracranial atherosclerotic diseases published in the world from 1900 to 2018, with a total citation frequency of 189 950, all of which were cited with a frequency of 22.43 and h-index 155. The output of related papers in China(excluding Taiwan, China) was on the rise as a whole. The total output of related papers was 1 157, ranking second in the world. In 1991, the first paper was published, reaching 14 in 2003, in 2014 it reached 105, in 2018 it reached 189, only 8 fewer than the United States, showing a momentum of rapid development. Among them, Capital Medical University had the largest contribution, ranking first in the global output of papers. However, the research quality of papers in China was still lower than that in the United States, which need to be further improved. Conclusion The research on intracranial atherosclerotic diseases in China starts late, but it has made rapid development in recent years. It has more and more influence in the world, and there is still a lack of high influence. In the future, it is necessary to further strengthen the hot research such as RCT, etiology, imaging diagnosis and treatment, from quantity improvement to quality improvement.