Abstract: Objective To study the effect and value of the five in one management of traditional Chinese medicine for type 2 diabetes patients signed by family doctors, and to provide theoretical support for clinical application. Methods From January 2018 to December 2018, 300 patients with type 2 diabetes who visited our center and signed a contract with a family doctor were selected and divided into control group and intervention group according to the random number method, 150 cases each. The control group adopted the family doctor contract system, and the intervention group joined the five-in-one service of traditional Chinese medicine on the basis of the control group. The blood sugar, blood lipid, liver function and kidney function were measured, and body mass index(BMI), knowledge of traditional Chinese medicine, awareness rate of traditional Chinese medicine service, contract rate and utilization rate of contract service were counted. Results The levels of TG, TC, HDL-C and LDL-C in the intervention group were lower than those in the control group(all P<0.05). The levels of FPG, 2 hPBG, HbA1 c and BMI in the intervention group were lower than those in the control group(all P<0.05). The levels of ALT, AST, serum creatinine and urea nitrogen in the intervention group were lower than those in the control group(all P<0.05). The awareness rate of TCM service in the intervention group was 88.67% higher than that in the control group 80.00%(χ²=4.264, P=0.039). In the intervention group, the 1+1+1 signing rate was 90.00% and the signing service utilization rate was 84.00% higher than that in the control group 81.33% and 67.33%(all P<0.05). Conclusion The application value of Chinese medicine five in one in type 2 diabetes patients signed by family doctors is significant. It can improve the level of blood glucose, blood lipid and liver function, improve the patients' cognition level of Chinese medicine, improve the signing rate and disease control rate.