Abstract: Objective To analyze the effects of modified preoperative bowel preparation in patients undergoing laparoscopic hysterectomy in gynecology department. Methods Ninety-six patients who underwent laparoscopic hysterectomy were enrolled in the study. They were divided into observation group and control group according to the random number table method, with 48 cases in each group. And they were given modified preoperative bowel preparation and routine preoperative bowel preparation respectively. The satisfaction of surgeons, perioperative parameters, occurrence of gastrointestinal symptoms, intestinal function recovery and levels of serum electrolytes before surgery and at 1 d after surgery were compared between the two groups. Results There was no significant difference in the satisfaction of surgeons between the two groups(all P>0.05). There were no significant differences in the incidence rate of involuntary defecation, intraoperative blood loss and operative time between the two groups(P>0.05), and the postoperative hospital stay was shorter than control group(P<0.05). There was no significant difference in the incidence rate of abdominal distension between the two groups(P>0.05), and the incidence rates of diarrhea, nausea and vomiting with 0.00%(0/48), 2.08%(1/48) and 4.17%(2/48) in observation group were lower than those in control group[10.42%(5/48), 12.50%(6/48) and 16.67%(8/48), χ²=5.275, 3.852, 4.019, all P<0.05]. There was no intestinal obstruction in the two groups, and the postoperative first intestine peristalsis time, postoperative first defecation time and postoperative first anal exhaust time with(15.16±1.79)h,(41.71±5.83) h and(18.26±2.78) h in observation group were shorter than those in control group with(17.35±1.58) h,(49.09±6.31) h and(21.12±2.97) h(t=6.355, 5.952, 4.871, all P<0.001). There were no significant changes in the levels of serum Na⁺, K⁺ and Cl^- in observation group at 1 d after surgery compared with those before surgery(all P>0.05). The levels of serum Na⁺, K⁺ and Cl^- in observation group were higher than in control group(all P<0.05). Conclusion Modified preoperative bowel preparation for gynecological laparoscopic hysterectomy can promote the recovery of intestinal function, and it is beneficial to patients with postoperative recovery, it is safe and feasible.