Intervention effects of TCM nursing in tumor patients undergoing continuous chemotherapy
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摘要: 目的 观察综合中医护理干预对恶性肿瘤患者化疗所致恶心呕吐(chemotherapy-induced nausea and vomiting,CINV)的干预效果。 方法 选取2017年6月—2018年12月在广西医科大学附属肿瘤医院接受持续多日化疗的恶性肿瘤患者70例,采用随机数字表法将其随机分为对照组(35例)和观察组(35例),对照组予以肿瘤科常规护理及预防CINV的常规方法,观察组在对照组基础上予以综合中医护理;比较2组CINV发生情况、化疗依从性、中文版正性负性情绪量表(positive and negative affect schedule,PANAS)评分、生活质量核心问卷(quality of life-core questionnaire,QLQ-C30)评定结果及护理满意度。 结果 观察组CINV发生率为45.71%,明显低于对照组的71.43%;且观察组CINV程度明显低于对照组(P<0.05)。观察组化疗依从性明显优于对照组(P<0.05)。干预后,观察组PANAS量表正性情绪评分[(24.12±4.68)分]明显高于对照组[(17.23±4.26)分,P<0.05],负性情绪评分[(35.75±4.86)分]明显低于对照组[(40.25±4.64)分],且QLQ-C30量表评定结果明显优于对照组(均P<0.05)。观察组护理满意度明显优于对照组,差异有统计学意义(P<0.05)。 结论 综合中医护理干预能够明显改善恶性肿瘤化疗患者CINV发生情况,提高患者化疗依从性,改善心理状态及生活质量。Abstract: Objective To observe the effects of integrated traditional Chinese medicine(TCM) nursing intervention on continuous chemotherapy-induced nausea and vomiting(CINV) in patients with malignant tumors. Methods Seventy patients with malignant tumors who underwent continuous chemotherapy in Affiliated Tumor Hospital of Guangxi Medical University from June 2017 to December 2018 were randomly divided into control group(35 cases) and observation group(35 cases). The control group were given routine nursing in Oncology Department and routine prevention of CINV, while the observation group were given integrated TCM nursing on the basis of control group. The occurrence of CINV, compliance of chemotherapy, Chinese version of Positive and Negative Affect Schedule(PANAS) scores, quality of life-core questionnaire(QLQ-C30) assessment results and nursing satisfaction were compared between the two groups. Results The incidence rate of CINV in the observation group was significantly lower than that in the control group(45.71% vs 71.43%), and CINV in the observation group was milder than that in the control group(P<0.05). The compliance of chemotherapy in the observation group was significantly better than that in control group(P<0.05). After intervention, the positive emotion score of PANAS scale in the observation group [(24.12±4.68) points] was significantly higher than that in the control group [(17.23±4.26) points, P<0.05], while the negative emotion score [(35.75±4.86) points] was significantly lower than that in control group [(40.25±4.64) points, P<0.05]. The assessment results of QLQ-C30 scale of the observation group were significantly better than those of the control group(P<0.05). The nursing satisfaction of the observation group was significantly better than that of the control group(P<0.05). Conclusion Integrated TCM nursing intervention can significantly reduce the occurrence of CINV in patients with malignant tumors undergoing chemotherapy, improve the patient's compliance of chemotherapy, psychological status and quality of life.
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