Abstract: Objective To investigate the effect of Duhuo Jisheng Decoction on postoperative lumbago of patients with intervertebral disc herniation. Methods From January 2017 to January 2019, 64 patients with residual lumbago after spinal endoscopic surgery for disc herniation were selected and divided into two groups according to different treatment methods. The control group received early rehabilitation training, and the research group received early rehabilitation combined with Duhuo Jisheng Decoction. Results The effective rate of 100.00% in the study group was higher than that in the control group(43.75%, χ²=25.043,P=0.000). The scores of physical life status, physical function, role function and social work in the study group were(84.00±4.40, 75.88±3.34, 85.00±4.08, 81.60±3.29) points, respectively, higher than those in the control group(75.83±5.06, 52.42±3.15, 76.00±3.19, 74.28±2.85) points(all P<0.05 respectively). VAS, ODI and ADL scores(0.83±0.64, 3.00±0.64, 3.00±0.58) in the study group were all lower than those in the control group(1.60±0.81, 3.83±0.69, 4.00±0.63), all P<0.05. Conclusion The application of Duhuo Jisheng Decoction in the treatment of residual lumbago after spinal endoscopy can promote the clinical recovery of the body function of patients, improve their quality of life, has an ideal therapeutic effect, and is worthy of application.