Abstract: Objective To understand the current status of diabetes pain in type 2 diabetes patients and analyze its influencing factors. Methods A total of 200 cases of patients with type 2 diabetes in the First Affiliated Hospital of Bengbu Medical College were chosen as the research object. The diabetes patients pain scale, general information questionnaire family per capita income, course, cultural degree, whether suffering from complications, age, sex, occupation, marital status, medical expense payment factors were analyzed. Results A total of 200 questionnaires were issued, 200 of which were valid. There were 87 cases under 45 years of age and 113 cases between 45 and 65 years of age. There were 88 cases with junior high school education or below, 75 cases with senior high school and technical secondary school education, and 37 cases with university education or above. There were 98 cases with a per capita monthly income of 3 000 yuan or less, and 102 cases with a per capita monthly income of 3,000 yuan or more. There were 66 patients with the course of disease less than 5 years, 70 patients with 5-10 years, and 64 patients with the course of disease more than 10 years. There were 132 cases with complications, and 68 cases without complications. Among the 200 subjects, more than half of the patients(55.41%) had diabetes pain of varying degrees(average score of diabetes pain≥2). In this survey, the pain score of diabetes was(2.600±1.040), which was in the middle level of the pain of diabetes. There were statistically significant differences in the average monthly income, course of disease, educational level and complications of diabetic patients(all P<0.05). Family per capita monthly income, course of disease, educational level and complications were the influencing factors of psychological distress score of patients with diabetes(all P<0.05). Conclusion Patients with type 2 diabetes have varying degrees of diabetes pain, and monthly income per family, course of disease, educational level and complications are the influencing factors of diabetes pain.