Observation on the clinical effect of traditional Chinese medicine in the treatment of joint swelling and pain after arthroscopy in knee osteoarthritis
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摘要:
目的 本研究对膝关节镜术后关节肿痛膝关节骨性关节炎(KOA)患者采用中药方剂治疗，通过观察用药后关节肿痛改善情况来评估临床效果，为中药治疗KOA患者膝关节镜术后关节肿痛提供一定依据。 方法 选取绍兴市中医院2018年2月—2020年2月收治的KOA膝关节镜术后关节肿痛患者72例，根据随机数字表法随机分为观察组和对照组各36例。对照组术后给予常规治疗，观察组在对照组常规治疗基础上给予自拟中药方剂消肿止痛方口服治疗。比较2组患者的治疗效果。 结果 术后第3、7和14天，观察组VAS评分分别为(4.91±0.73)分、(3.17±0.81)分、(1.75±0.76)分，对照组分别为(5.68±0.72)分、(4.51±0.79)分、(3.11±0.77)分，2组均较术前明显降低(均P < 0.05)，观察组VAS评分明显低于对照组(均P < 0.01);对照组术后第3、7和14天膝关节肿胀值分别为(43.12±2.16)mm、(32.23±1.37)mm和(19.73±0.85)mm，观察组分别为(36.52±2.13)mm、(19.72±1.53)mm、(8.42±0.93)mm; 观察组术后第3、7和14天患侧膝关节肿胀值明显低于对照组(均P < 0.01)。 结论 中药治疗对KOA患者膝关节镜术后关节肿痛具有很好的临床疗效，能显著改善膝关节镜术后关节肿胀和疼痛，值得在临床上推广使用。 Abstract:Objective In this study, traditional Chinese medicine prescriptions were used to treat patients with joint swelling and pain after knee arthroscopy in knee osteoarthritis(KOA) patients, and the clinical effect was evaluated by observing the improvement of joint swelling and pain after medication, so as to provide a certain basis for the treatment of joint swelling and pain after knee arthroscopy in patients with knee arthroscopy with traditional Chinese medicine. Methods A total of 72 patients with joint swelling and pain after KOA arthroscopy admitted to Shaoxing Hospital of Traditional Chinese Medicine from February 2018 to February 2020 were randomly divided into observation group and control group with 36 cases in each group according to random number table method. The control group was given routine treatment after surgery, and the observation group was given oral treatment of self-designed traditional Chinese medicine prescription Xiaozhong Zhitong on the basis of routine treatment in the control group. The therapeutic effect of 2 groups was compared. Results On day 3, 7 and 14 after surgery, the VAS scores of the observation group were (4.91±0.73) points, (3.17±0.81) points and (1.75±0.76) points, respectively, while those of the control group were (5.68±0.72) points, (4.51±0.79) points and (3.11±0.77) points, respectively. The VAS scores of the observation group were significantly lower than those of the control group (all P < 0.05). The swelling values of knee joint in the control group on the 3, 7 and 14 days after operation were (43.12±2.16) mm, (32.23±1.37) mm and (19.73±0.85) mm respectively, while those in the observation group were (36.52±2.13) mm, (19.73±1.53) mm and (8.42±0.93) mm respectively. The swelling value of the affected knee joint in the observation group on the 3, 7 and 14 days after operation was significantly lower than that in the control group (all P < 0.01). Conclusion Traditional Chinese medicine has a good clinical effect on joint swelling and pain after knee arthroscopy in patients with KOA, and can significantly improve the joint swelling and pain after knee arthroscopy. It is worthy of clinical application. -
表 1 2组关节肿痛患者VAS评分比较(x±s，分)
组别 例数 术前 术后第3天 术后第7天 术后第14天 F值 P值 观察组 36 7.57±0.53 4.91±0.73a 3.17±0.81b 1.75±0.76b 13.258 < 0.001 对照组 36 7.51±0.64 5.68±0.72a 4.51±0.79a 3.11±0.77b 9.782 < 0.001 t值 0.437 4.506 7.106 7.542 P值 0.663 < 0.001 < 0.001 < 0.001 注：与同组术前比较，aP < 0.05，bP < 0.01。 
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表 2 2组关节肿痛患者患侧膝关节肿胀值比较(x±s，mm)
组别 例数 术前 术后第3天 术后第7天 术后第14天 F值 P值 观察组 36 43.11±2.24 36.52±2.13a 19.73±1.53b 8.42±0.93b 15.986 < 0.001 对照组 36 42.91±2.18 43.12±2.16 32.23±1.37a 19.72±0.85b 12.845 < 0.001 t值 0.384 13.054 36.519 53.861 P值 0.702 < 0.001 < 0.001 < 0.001 注：与同组术前比较，aP < 0.05，bP < 0.01。
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