口服盐酸利多卡因胶浆联合磷酸钠盐在肠镜检查中的效果观察

柴先灯; 李伦兰; 杨桂芳; 李杨; 孙斌

doi:10.16766/j.cnki.issn.1674-4152.002073

口服盐酸利多卡因胶浆联合磷酸钠盐在肠镜检查中的效果观察

doi: 10.16766/j.cnki.issn.1674-4152.002073

1.
安徽医科大学第一附属医院消化内科，安徽合肥 230022
2.
安徽医科大学第一附属医院人力资源部，安徽合肥 230022

基金项目:

国家自然科学基金项目 61976007

详细信息

通讯作者:
李伦兰，E-mail：lilunlan@aliyun.com

中图分类号: R473.57 R574
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- 文章访问数: 378
- HTML全文浏览量: 243
- PDF下载量: 5
- 被引次数: 0
出版历程
- 收稿日期: 2021-02-04
- 网络出版日期: 2022-02-16

The effect of oral lidocaine hydrochloride mucilage combined with sodium phosphate in colonoscopy

1.
Gastroenterology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China

摘要

摘要: 目的探讨口服盐酸利多卡因胶浆联合磷酸钠盐溶液肠道准备方法在普通肠镜检查肠道准备中的应用效果，以提高肠镜检查效率及质量。方法选择安徽医科大学第一附属医院2020年4—6月接受普通结肠镜检查的293例患者为研究对象，按随机数字表法随机分为观察组(145例)和对照组(148例)。对照组患者采用传统方法，即分2次服用磷酸钠盐行肠道准备，观察组患者在对照组的基础上于检查前4~6 h加服20 mL盐酸利多卡因胶浆。采用Morisky服药依从性量表、波士顿肠道准备量表、Bubble气泡评分标准、疼痛数字评分法比较2组患者在服药依从性、肠道准备清洁度、肠道气泡评分、检查中患者疼痛程度以及退镜时间、息肉检出率上的差异。结果 2组患者服药依从性、肠道清洁度、疼痛程度、息肉检出率比较，差异无统计学意义(均P＞0.05)。观察组患者肠道气泡评分为(2.57±0.69)分，高于对照组患者[(2.24±0.78)分]，差异有统计学意义(t=3.833, P＜0.001)。观察组患者退镜时间为(6.82±1.23)min，短于对照组患者[(7.88±1.77)min]，差异有统计学意义(t=5.941, P＜0.001)。结论口服盐酸利多卡因胶浆联合磷酸钠盐肠道准备方法，能够有效减少肠道内的气泡量，缩短肠镜检查时间，提高肠镜检查效率及质量。
- 盐酸利多卡因胶浆 /
- 结肠镜 /
- 肠道准备 /
- 磷酸钠盐 /
- 祛泡
Abstract: Objective To explore the application effect of oral lidocaine hydrochloride mucilage combined with sodium phosphate solution in bowel preparation in common colonoscopy and to improve the efficiency and quality of colonoscopy. Methods Total 293 patients who underwent general colonoscopy in our hospital from April to June 2020 were enrolled and randomly divided into two groups according to the random number table method, including 145 cases in the experimental group and 148 cases in the control group. The patients in the control group used the traditional method of taking sodium phosphate in two doses for bowel preparation. The patients in the experimental group were given 20 mL lidocaine hydrochloride mucilage 4-6 hours before the examination on the basis of the control group. Morisky Medication Compliance Scale, Boston Bowel Intestinal Preparation Scale, Bubble Score, and Pain Numerical Score were used to compare the medication compliance, cleanliness of intestinal preparation, intestinal bubble score, and the degree of pain during the examination between the two groups of patients. Results There were no significant difference in medication compliance, intestinal cleanliness, pain degree, and polyp detection rate between the two groups of patients (all P>0.05). The score of the intestinal bubble score of the test group was (2.57±0.69) points, which was higher than the score of the control group [(2.24±0.78) points], and the difference was statistically significant (t=3.833, P < 0.001). The time to withdraw the lens in the experimental group was (6.82±1.23) minutes, which was less than (7.88±1.77) minutes in the control group, and the difference was statistically significant (t=5.941, P < 0.001). Conclusion The intestinal preparation method of oral lidocaine hydrochloride mucilage combined with sodium phosphate can effectively reduce the amount of bubbles in the intestine, shorten the time of colonoscopy, and improve the efficiency and quality of colonoscopy.
- Lidocaine hydrochloride mucilage /
- Colonoscopy /
- Bowel preparation /
- Sodium phosphate /
- Dispelling bubbles

HTML全文

图 1 2组行普通结肠镜检查患者肠道准备后电子结肠镜检查图片

上排为对照组检查图片；下排为观察组检查图片。

下载: 全尺寸图片幻灯片

表 1 2组行普通结肠镜检查患者一般临床资料比较

组别	例数	性别(例)		年龄(x±s, 岁)	便秘史(例)	就诊类型(例)
组别	例数	男性	女性	年龄(x±s, 岁)	便秘史(例)	门诊	住院
观察组	145	68	77	46.72±16.45	13	75	70
对照组	148	73	75	49.63±17.72	18	80	68
统计量		0.173^a		1.456^b	0.791^a	0.160^a
P值		0.678		0.146	0.374	0.690
注：^a为χ²值，^b为t值。

下载: 导出CSV

表 2 2组行普通结肠镜检查患者服药依从性、肠道清洁度评分、肠道祛泡效果评分比较

组别	例数	服药依从性(例)		清洁度评分(x±s，分)	气泡量评分(x±s，分)
组别	例数	优良	差	清洁度评分(x±s，分)	气泡量评分(x±s，分)
观察组	145	135	10	6.72±1.34	2.57±0.69
对照组	148	142	6	6.85±1.22	2.24±0.78
统计量		1.146^a		0.869^b	3.833^b
P值		0.284		0.386	＜0.001
注：^a为χ²值，^b为t值。

下载: 导出CSV

表 3 2组行普通结肠镜检查患者退镜时间、息肉检出率、疼痛程度比较

组别	例数	退镜时间(x±s，min)	息肉检出[例(%)]	疼痛评分(x±s，分)
观察组	145	6.82±1.23	43(29.66)	3.25±1.02
对照组	148	7.88±1.77	34(22.97)	3.37±1.10
统计量		5.941^a	1.688^b	0.968^a
P值		＜0.001	0.194	0.334
注：^a为t值，^b为χ²值。

下载: 导出CSV

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