高分化子宫内膜样癌的超声诊断与病理结果对照分析

蔡婷婷; 徐亚芬; 舒艳; 施春霞; 陆文明; 茆丽敏; 刘明松

doi:10.16766/j.cnki.issn.1674-4152.002108

高分化子宫内膜样癌的超声诊断与病理结果对照分析

doi: 10.16766/j.cnki.issn.1674-4152.002108

1.
湖州市妇幼保健院超声科，浙江湖州 313000
2.
湖州第一人民医院超声科，浙江湖州 313000

基金项目:

浙江省医药卫生科技计划项目 2019PY015

浙江省湖州市科技计划项目 2019GY37

详细信息

通讯作者:
刘明松, E-mail: 46202400@qq.com

中图分类号: R737.33 R445.1
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- 被引次数: 0
出版历程
- 收稿日期: 2020-05-28
- 网络出版日期: 2022-02-15

Ultrasound diagnosis and pathological analysis of highly differentiated endometrial carcinoma

1.
Department of Ultrasound, Huzhou Maternal and Child Health Hospital, Huzhou, Zhejiang 313000, China

摘要

摘要: 目的通过分析高分化子宫内膜样癌患者的超声特征，评估超声在子宫内膜样癌浸润程度方面的诊断符合率。方法回顾性纳入2016年1月—2019年10月期间湖州市妇幼保健院收治的高分化子宫内膜样癌患者42例为研究组，另选取该时期收治的子宫内膜增生患者30例为对照组。对比2组患者超声测得的子宫内膜厚度、阻力指数(resistance index，RI)、搏动指数(pulsation index，PI)；以病理诊断作金标准，分析超声检查在研究组患者肌层浸润程度方面的诊断符合率；对比3组不同肌层浸润程度患者超声检测结果。结果研究组患者的子宫内膜厚度为(2.09±0.64)mm，明显比对照组[(1.76±0.53)mm]高(t=2.313，P=0.024)；研究组的RI、PI指数分别是0.68±0.25、0.47±0.12，明显比对照组(1.03±0.34、0.66±0.13)低(t=5.037、6.397，均P < 0.001)。研究组无、浅、深肌层浸润患者子宫内膜厚度分别为(2.02±0.62)mm、(1.97±0.61)mm、(2.90±0.00)mm，RI指数依次为0.64±0.23、0.65±0.22、1.02±0.25，PI指数分别为0.46±0.11、0.44±0.11、0.64±0.01；深肌层浸润组子宫内膜厚度明显比无、浅肌层浸润组高(均P < 0.05)，而该组患者的RI和PI指数则明显高于另外2组(均P < 0.05)。超声在高分化子宫内膜样癌无、浅、深肌层浸润患者中的诊断符合率依次是89.3%、80.0%、75.0%。结论超声对高分化子宫内膜样癌患者的诊断与其病理结果呈现出较高的一致性，值得临床应用。
- 高分化 /
- 子宫内膜癌 /
- 超声 /
- 病理检查
Abstract: Objective To evaluate the diagnostic coincidence rate of ultrasound on the degree of endometrial carcinoma infiltration by analysing the characteristics of patients with highly differentiated endometrial carcinoma. Methods A total of 42 patients with highly differentiated endometrial cancer admitted at our hospital during January 2016 to October 2019 were retrospectively included as study groups, and 30 patients with endometrial hyperplasia admitted at our hospital during the same period were selected as control groups. The endometrial thickness, resistance index (RI) and pulsation index (PI) in both groups were measured by ultrasound. According to the gold standard of pathological diagnosis, the diagnostic coincidence rate of ultrasound in the degree of myometrial invasion in the study group was analysed. The ultrasonic test results of three groups with different muscle layer infiltration degree were compared. Results The endometrial thickness of the study group was (2.09±0.64) mm, which was significantly higher than that of the control group [(1.76±0.53) mm, t=2.313, P=0.024]. The RI and PI of the study group were 0.68±0.25 and 0.47±0.12, which were significantly lower than those of the control group (1.03±0.34, 0.66±0.13, t=5.037, 6.397, both P < 0.001). The endometrial thickness were (2.02±0.62) mm, (1.97±0.61) mm and (2.90±0.00) mm; the RI were 0.64±0.23, 0.65±0.22 and 1.02±0.25; and the PI were 0.46±0.11, 0.44±0.11 and 0.64±0.01, respectively. The endometrial thickness in the deep myometrial infiltration group was significantly higher than that in the superficial myometrial infiltration group (all P < 0.05), whereas the RI and PI of patients in this group were significantly higher than those in the other two groups (all P < 0.05). The diagnostic coincidence rates of ultrasound in patients with no, shallow and deep myometrial infiltration with highly differentiated endometrial carcinoma were 89.3%, 80.0% and 75.0%, respectively. Conclusion The diagnosis of highly differentiated endometrial cancer patients by ultrasound shows high consistency with the pathological results, which is worthy of clinical application.
- High differentiation /
- Endometrial carcinoma /
- Ultrasound /
- Pathological examination

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表 1 2组患者超声指标比较(x±s)

组别	例数	内膜厚度(mm)	RI	PI
研究组	42	2.09±0.64	0.68±0.25	0.47±0.12
对照组	30	1.76±0.53	1.03±0.34	0.66±0.13
t值		2.313	5.037	6.397
P值		0.024	< 0.001	< 0.001

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表 2 不同肌层浸润程度高分化子宫内膜样癌患者的超声指标比较(x±s)

组别	例数	内膜厚度(mm)	RI	PI
无肌层浸润	28	2.02±0.62	0.64±0.23	0.46±0.11
浅肌层浸润	10	1.97±0.61	0.65±0.22	0.44±0.11
深肌层浸润	4	2.90±0.00^ab	1.02±0.25^ab	0.64±0.01^ab
F值		4.147	4.757	5.764
P值		0.023	0.014	0.006
注：与无肌层浸润组比较，^aP < 0.05；与浅肌层浸润组比较，^bP < 0.05。

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表 3 研究组高分化子宫内膜样癌患者病理诊断结果(例)

检查方法		病理结果			合计
检查方法		无肌层浸润	浅肌层浸润	深肌层浸润	合计
超声	无肌层浸润	25	1	0	26
	浅肌层浸润	3	8	1	12
	深肌层浸润	0	1	3	4
合计		28	10	4	42

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