脚踏车运动疗法与加巴喷丁治疗血液透析伴不宁腿综合征患者的应用价值

夏敏; 陈富星

doi:10.16766/j.cnki.issn.1674-4152.002456

脚踏车运动疗法与加巴喷丁治疗血液透析伴不宁腿综合征患者的应用价值

doi: 10.16766/j.cnki.issn.1674-4152.002456

夏敏¹,
陈富星^2, ,

1.
宁波市北仑区人民医院肾内科，浙江宁波 330206
2.
宁波市北仑区人民医院放射科，浙江宁波 330206

基金项目:

浙江省医药卫生科技计划项目 2019KY654

详细信息

通讯作者:
陈富星，E-mail：chenfux@163.com

中图分类号: R692.5 R459.5
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- 文章访问数: 112
- HTML全文浏览量: 72
- PDF下载量: 1
- 被引次数: 0
出版历程
- 收稿日期: 2021-01-06
- 网络出版日期: 2022-09-05

Application value of bicycle exercise therapy and gabapentin in the treatment of haemodialysis patients with restless legs syndrome

XIA Min¹,
CHEN Fu-xing^{2
, ,}

1.
Department of Nephrology, People's Hospital of Beilun District, Ningbo, Zhejiang 330206, China

摘要

摘要: 目的分析脚踏车运动疗法与加巴喷丁治疗血液透析伴不宁腿综合征(restless legs syndrome，RLS)患者的效果及对睡眠质量、生活质量的影响。方法将宁波市北仑区人民医院2018年12月—2020年6月间收治的60例行血液透析合并RLS患者按随机信封法分为观察组和对照组，每组各30例；对照组采用加巴喷丁治疗，观察组采用脚踏车运动疗法与加巴喷丁治疗；治疗前和治疗12周后对患者的病情严重程度、睡眠质量和生活质量进行调查。结果治疗后观察组患者国际下肢不宁腿综合征等级评估量表(IRLS)、阿森斯失眠量表(AIS)和匹兹堡睡眠质量指数量表(PSQI)评分明显低于对照组[(7.03±1.83)分vs.(13.64±2.11)分，(4.12±1.11)分vs.(5.99±0.94)分，(7.03±0.75)分vs.(9.13±0.88)分]，且差异有统计学意义(均P < 0.05)；治疗后观察组患者健康调查量表(SF-36)心理维度评分和SF-36生理维度评分明显高于对照组[(78.12±6.22)分vs.(70.04±5.33)分，(79.98±7.48)分vs.(69.82±6.32)分]，且差异有统计学意义(均P < 0.05)。结论采用脚踏车运动疗法与加巴喷丁联合应用可显著改善血液透析伴RLS患者的病情严重程度，提高患者睡眠质量和生活质量。
- 脚踏车运动疗法 /
- 加巴喷丁 /
- 血液透析 /
- 不宁腿综合征 /
- 睡眠质量 /
- 生活质量
Abstract: Objective To analyse the effects of cycling exercise therapy and gabapentin in the treatment of haemodialysis patients with restless legs syndrome (RLS), and determine their effects on sleep quality and quality of life. Methods Sixty haemodialysis patients with RLS admitted in People's Hospital of Beilun District from December 2018 to June 2020 were randomly divided into the observation group and control group. The control group was treated with gabapentin, and the observation group was treated with bicycle exercise therapy and gabapentin. The clinical efficacy, sleep quality and quality of life were investigated before and after 12 weeks of treatment. Results After treatment, the IRLS scale score, AIS scale score and PSQI scale score of the observation group were significantly lower than those of the control group [(7.03±1.83) points vs. (13.64±2.11) points, (4.12±1.11) points vs. (5.99±0.94) points, (7.03±0.75) points vs. (9.13±0.88) points, respectively], and the differences were statistically significant (all P < 0.05). After treatment, SF-36 psychological dimension scores and SF-36 physiological dimension scores of patients in the observation group were higher than those in the control group [(78.12±6.22) points vs. (70.04±5.33) points, (79.98±7.48) points vs. (69.82±6.32) points, respectively], and the differences were statistically significant (all P < 0.05). Conclusion The combined application of bicycle exercise therapy and gabapentin can significantly improve the efficacy of haemodialysis patients with RLS, as well as improve the quality of sleep and quality of life.
- Bicycle exercise therapy /
- Gabapentin /
- Haemodialysis /
- Restless legs syndrome /
- Sleep quality /
- Quality of life

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表 1 2组血液透析合并RLS患者IRLS评分比较(x±s，分)

Table 1. Comparison of IRLS score between two groups of hemodialysis patients with RLS(x±s, scores)

组别	例数	治疗前	治疗后	t值	P值
观察组	30	24.48±3.12	7.03±1.83	26.424	< 0.001
对照组	30	24.51±2.99	13.64±2.11	16.269	< 0.001
t值		2.002	12.962
P值		0.970	< 0.001

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表 2 2组血液透析合并RLS患者睡眠质量比较(x±s，分)

Table 2. Comparison of sleep quality between two groups of hemodialysis patients with RLS(x±s, scores)

组别	例数	AIS评分		t值	P值	PSQI评分		t值	P值
组别	例数	治疗前	治疗后	t值	P值	治疗前	治疗后	t值	P值
观察组	30	9.93±1.02	4.12±1.11	21.110	< 0.001	12.54±1.21	7.03±0.75	21.200	< 0.001
对照组	30	9.96±1.19	5.99±0.94	13.874	< 0.001	12.68±1.15	9.13±0.88	13.428	< 0.001
t值		0.105	18.348			0.459	9.948
P值		0.917	< 0.001			0.648	< 0.001

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表 3 2组血液透析合并RLS患者生活质量比较(x±s，分)

Table 3. Quality of life of hemodialysis patients with RLS in two groups(x±s, scores)

组别	例数	SF-36心理维度评分		t值	P值	SF-36生理维度评分		t值	P值
组别	例数	治疗前	治疗后	t值	P值	治疗前	治疗后	t值	P值
观察组	30	59.38±4.95	78.12±6.22	12.912	< 0.001	45.73±8.39	79.98±7.48	16.690	< 0.001
对照组	30	60.11±5.39	70.04±5.33	7.216	< 0.001	46.01±9.18	69.82±6.32	11.701	< 0.001
t值		0.546	5.403			0.123	5.683
P值		0.587	< 0.001			0.902	< 0.001

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