Improvement of mood, psychological resilience and sleep quality in patients with first-episode depression by networked mindfulness-based cognitive group therapy
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摘要:
目的 探索网络静观认知团体治疗对首发抑郁症患者抑郁、焦虑、心理弹性和睡眠质量的影响。 方法 选择2020年1月—2021年9月于杭州市第七人民医院就诊的84例首发抑郁症患者,根据随机数字表法分为对照组(药物治疗,40例)和干预组(药物+网络静观团体治疗,44例)。观察2组8周治疗后抑郁评分、焦虑评分、心理弹性评分和睡眠质量评分变化。 结果 经过8周治疗后,2组抑郁评分、焦虑评分、心理弹性评分、睡眠质量评分均较治疗前改善(均P<0.001),治疗后组间比较发现干预组抑郁评分[(5.84±3.50)分]、焦虑评分[(8.07±2.65)分]、心理弹性评分[(80.68±6.66)分]和睡眠质量评分[(5.93±1.87)分]均优于对照组[(9.38±4.54)分、(11.23±4.88)分、(72.28±5.29)分、(7.73±2.03)分,均P<0.001]。患者基线抑郁评分与心理弹性评分呈负相关(r=-0.747, P<0.001),与睡眠质量评分呈正相关(r=0.892, P<0.001)。 结论 网络静观认知团体治疗可缓解首发抑郁症患者抑郁、焦虑情绪,提高心理弹性,改善睡眠质量。 Abstract:Objective To explore the effects of networked mindfulness-based cognitive group therapy on depression, anxiety, psychological resilience levels and sleep quality in patients with first-episode depression. Methods Eighty-four patients with first-episode depression who attended the Hangzhou Seventh People ' s Hospital from January 2020 to September 2021 were selected and randomly divided into a control group (conventional medication, n=40) and an intervention group (medication+networked mindfulness-based cognitive group therapy, n=44) according to a random number table. Changes in depression, anxiety, psychological resilience and sleep quality were explored in the two groups after 8 weeks of treatment. Results After 8 weeks of treatment, the scores of depression, anxiety, psychological resilience scores and sleep quality significantly improved in both the control and intervention groups compared with those before the treatment (each P < 0.001). Comparison between groups after treatment revealed that the scores of depression, anxiety, psychological resilience scores and sleep quality in the intervention group [(5.84±3.50) points, (8.07±2.65) points, (80.68±6.66) points, (5.93±1.87) points] were better than those in the control group [(9.38±4.54) points, (11.23±4.88) points, (72.28±5.29) points, (7.73±2.03) points, all P < 0.001]. The scores of depression at baseline were negatively correlated with their psychological resilience scores (r=-0.747, P < 0.001) and positively correlated with their sleep quality scores (r=0.892, P < 0.001). Conclusion Networked mindfulness-based cognitive group therapy can alleviate depression and anxiety, increase psychological resilience and improve sleep quality in patients with first-episode depression. -
Key words:
- Depression /
- Group psychotherapy /
- Network
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表 1 2组首发抑郁症患者一般资料比较
Table 1. Comparison of general data of two groups of patients with first episode depressionn
组别 例数 年龄(x±s,岁) 性别(例) 受教育年限(x±s,年) 女性 男性 对照组 40 29.83±4.12 25 15 14.55±1.32 干预组 44 28.95±3.95 29 15 13.89±1.70 统计量 0.989a 0.106b 1.983a P值 0.326 0.821 0.051 注:a为t值,b为χ2值。 表 2 2组首发抑郁症患者治疗前后HAMD、HAMA、CD-RISC及PSQI评分比较(x±s,分)
Table 2. Comparison of HAMD, HAMA, CD-RISC and PSQI scores before and after treatment in two groups of patients with first episode depression (x±s, points)
组别 例数 HAMD HAMA CD-RISC PSQI 治疗前 治疗后 治疗前 治疗后 治疗前 治疗后 治疗前 治疗后 对照组 40 22.08±3.23 9.38±4.54a 24.45±3.21 11.23±4.88a 43.28±5.96 72.28±5.29a 12.15±2.64 7.73±2.03a 干预组 44 21.48±3.43 5.84±3.50a 23.61±4.61 8.07±2.65a 44.82±6.83 80.68±6.66a 12.50±3.48 5.93±1.87a t值 0.82 3.966 0.972 3.634 1.098 6.367 0.515 4.216 P值 0.415 < 0.001 0.334 0.001 0.275 < 0.001 0.608 < 0.001 注:与同组治疗前比较,aP<0.001。 表 3 首发抑郁症患者基线HAMD评分、CD-RISC评分及PSOI评分间的相关性(r值)
Table 3. Correlation between baseline HAMD score, CD-RISC score and PSOI score in patients with first episode depression (r values)
项目 HAMD PSQI CD-RISC HAMD 1.000 PSQI 0.892 1.000 CD-RISC -0.747 -0.652 1.000 注:控制变量年龄和受教育年限。均P<0.001。 -
[1] ZHANG Z J, ZHANG L L, ZHANG G R, et al. The effect of CBT and its modifications for relapse prevention in major depressive disorder: A systematic review and meta-analysis[J]. BMC Psychiatry, 2018, 18(1): 50. doi: 10.1186/s12888-018-1610-5 [2] PITSILLOU E, BRESNEHAN S M, KAGARAKIS E A, et al. The cellular and molecular basis of major depressive disorder: Towards a unified model for understanding clinical depression[J]. Mol Bio Rep, 2020, 47(1): 753-770. doi: 10.1007/s11033-019-05129-3 [3] HOFMANN S G, GOMEZ A F. Mindfulness-based interventions for anxiety and depression[J]. Psychiat Clin North Am, 2017, 40(4): 739-749. doi: 10.1016/j.psc.2017.08.008 [4] SEGAL Z V, DIMIDJIAN S, BECK A, et al. Outcomes of online mindfulness-based cognitive therapy for patients with residual depressive symptoms: A randomized clinical trial[J]. JAMA Psychiatry, 2020, 77(6): 563-573. doi: 10.1001/jamapsychiatry.2019.4693 [5] APOLINARIO-HAGEN J, DRUGE M, FRITSCHE L. Cognitive behavioral therapy, mindfulness-based cognitive therapy and acceptance commitment therapy for anxiety disorders: Integrating traditional with digital treatment approaches[J]. Adv Exp Med Biol, 2020, 119(1): 291-329. [6] HAMILTON M. A rating scale for depression[J]. J Neurol Neurosur Psychiat, 1960, 23: 56-62. doi: 10.1136/jnnp.23.1.56 [7] HAMILTON M. The assessment of anxiety states by rating[J]. Brit J Med Psychol, 1959, 32(1): 50-55. doi: 10.1111/j.2044-8341.1959.tb00467.x [8] CONNOR K M, DAVIDSON J R. Development of a new resilience scale: The Connor-Davidson Resilience Scale (CD-RISC)[J]. Depress Anxiety, 2003, 18(2): 76-82. doi: 10.1002/da.10113 [9] WANG L, SHI Z B, ZHANG Y Q, et al. Psychometric properties of the 10-item Connor-Davidson resilience scale in Chinese earthquake victims[J]. Psychiatry Clin Neurosci, 2010, 64(5): 499-504. doi: 10.1111/j.1440-1819.2010.02130.x [10] 刘贤臣, 唐茂芹, 胡蕾, 等. 匹兹堡睡眠质量指数的信度和效度研究[J]. 中华精神科杂志, 1996, 29(2): 103-107. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHMA199602018.htmLIU X C, TANG M Q, HU L, et al. Reliability and validity of the Pittsburgh sleep quality index[J]. Chinese Journal of Psychiatry, 1996, 29(2): 103-107. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHMA199602018.htm [11] DE KLERK-SLUIS J M, HUIJBERS M J, LOCKE S, et al. Factors associated with relapse and recurrence of major depressive disorder in patients starting mindfulness-based cognitive therapy[J]. Depress Anxiety, 2022, 39(2): 113-122. doi: 10.1002/da.23220 [12] 王晓丝, 岳建新, 栗雪琪, 等. 团体正念训练对神经性厌食躯体化及住院依从性影响的研究[J]. 齐齐哈尔医学院学报, 2021, 42(4): 360-364. doi: 10.3969/j.issn.1002-1256.2021.04.030WANG X S, YUE J X, LI X Q, et al. A study on the influence of groupmindfulness training on somatization and hospitalization compliance in patients with anorexia nervosa[J]. Journal of Qiqihar Medical University, 2021, 42(4): 360-364. doi: 10.3969/j.issn.1002-1256.2021.04.030 [13] BURGESS E E, SELECHEN S, DIPLOCK B D, et al. A brief mindfulness-based cognitive therapy (MBCT) intervention as a population-level strategy for anxiety and depression[J]. Int J Cogn Ther, 2021, 14(2): 380-398. doi: 10.1007/s41811-021-00105-x [14] WONG S Y S, SUN Y Y, CHAN A T Y, et al. Treating subthreshold depression in primary care: A randomized controlled trial of behavioral activation with mindfulness[J]. Ann Fam Med, 2018, 16(2): 111-119. doi: 10.1370/afm.2206 [15] 石银燕, 夏泳. 团体心理治疗对首发精神分裂症患者认知功能、社会功能及疗效的影响[J]. 中华全科医学, 2018, 16(6): 957-960. doi: 10.16766/j.cnki.issn.1674-4152.000263SHI Y Y, XIA Y. Effect of group psychotherapy on cognitive, social functions and curative efficacy in first-episode schizophrenia patients[J]. Chinese Journal of General Practice, 2018, 16(6): 957-960. doi: 10.16766/j.cnki.issn.1674-4152.000263 [16] 赵辉. 支持性团体心理治疗干预社区卫生服务中心老年住院患者焦虑抑郁的效果评价[J]. 中华全科医学, 2019, 17(4): 614-618. doi: 10.16766/j.cnki.issn.1674-4152.000749ZHAO H. Effect of supportive group psychotherapy on anxiety and depression of elderly inpatients in community health service centers[J]. Chinese Journal of General Practice, 2019, 17(4): 614-618. doi: 10.16766/j.cnki.issn.1674-4152.000749 [17] CILLESSEN L, VAN DE VEN M O M, COMPEN F R, et al. Predictors and effects of usage of an online mindfulness intervention for distressed cancer patients: Usability study[J]. J Med Internet Res, 2020, 22(10): e17526. DOI: 10.2196/17526. [18] CILLESSEN L, SCHELLEKENS M P J, VAN DE VEN M O M, et al. Consolidation and prediction of long-term treatment effect of group and online mindfulness-based cognitive therapy for distressed cancer patients[J]. Acta oncologica, 2018, 57(10): 1293-1302. doi: 10.1080/0284186X.2018.1479071 [19] 刘华华, 蒋红, 丁晓芸, 等. 网络团体认知行为治疗对肺癌术后化疗患者焦虑抑郁的影响[J]. 护理学杂志, 2022, 37(1): 72-74. https://www.cnki.com.cn/Article/CJFDTOTAL-HLXZ202201021.htmLIU H H, JIANG H, DING X Y, et al. Impact of internet-based group cognitive behavioral therapy on anxiety and depression of lung cancer patients undergoing postoperative chemotherapy[J]. Journal of Nursing Science, 2022, 37(1): 72-74. https://www.cnki.com.cn/Article/CJFDTOTAL-HLXZ202201021.htm [20] BISSELING E, CILLESSEN L, SPINHOVEN P, et al. Development of the therapeutic alliance and its association with internet-based mindfulness-based cognitive therapy for distressed cancer patients: Secondary analysis of a multicenter randomized controlled trial[J]. J Med Internet Res, 2019, 21(10): e14065. DOI: 10.2196/14065.
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