Healthy examination results and 5-year follow-up analysis of the elderly in a community of Pudong New Area, Shanghai
-
摘要:
目的 分析65岁及以上老年人健康体检结果及慢性病发生率的动态变化,为制定区域内老年人健康管理方案提供参考。 方法 选取上海市浦东新区某社区2014年1月—2019年12月连续每年参加健康体检的年龄≥65岁老年人2 846例为研究对象,并排除恶性肿瘤及严重的血液系统疾病和肝、肾疾病者。所有研究对象采集标本前1 d保持清淡饮食,在采集标本前24 h不进行剧烈运动,并在采集标本前禁食12 h后于清晨空腹采血。由专业体检医师测量身高、体重和血压,计算BMI,采集一般资料、生化指标及腹部超声检查资料后进行对比分析。 结果 与2014年相比,2 846例老年人2019年血压、血糖、糖化血红蛋白、低密度脂蛋白、甘油三酯、总胆固醇及血尿酸水平均明显升高(均P<0.05)。此外,2 846例老年人2019年高血压、高甘油三酯血症、高胆固醇血症及高尿酸血症检出率(33.1%、28.3%、24.2%、23.8%、28.4%)均较2014年(22.6%、18.1%、15.1%、14.9%、19.2%)显著增加(均P<0.05)。 结论 浦东新区社区65岁及以上老年人群代谢指标水平及高血压、糖尿病、高脂血症和高尿酸血症的检出率呈现出上升的动态变化,提示需对社区老年人群高血压和糖脂代谢异常进行早期干预和健康宣教。 Abstract:Objective To investigate dynamic changes in the results of healthy examination and incidence of chronic diseases in the elderly aged 65 and then to provide a reference for the formulation of regional health management plan for the elderly. Methods A total of 2 846 elderly people over 65 in a community of Pudong New Area in Shanghai who continued to participate in healthy examination from January 2014 to December 2019 were selected as the research subjects. Subjects with malignant tumours, serious blood system diseases and liver and kidney diseases were excluded. All subjects maintained a bland diet one day before sample collection, did not undergo strenuous exercise 24 hours before sample collection and fasted for 12 hours before sample collection. Blood samples were obtained while their stomachs were empty in the morning. Height, weight, body mass index and blood pressure were measured by professional physical examination doctors, and general data were collected. Biochemical indexes and abdominal ultrasound examination data were collected and analysed. Results The blood pressure, blood glucose, glycosylated haemoglobin, low-density lipoprotein, triglyceride, total cholesterol and blood uric acid levels in the elderly people in 2019 significantly increased relative to those in 2014 (all P < 0.05). In addition, the detection rates of hypertension, diabetes, hyperlipidaemia, hyperuricaemia and hyperuricemia in 2 846 elderly people in 2019 (33.1%, 28.3%, 24.2%, 23.8%, 28.4%) were significantly higher than those in 2014 (22.6%, 18.1%, 15.1%, 14.9%, 19.2%, all P < 0.05). Conclusion The levels of metabolic indexes and the detection rates of hypertension, diabetes, hyperlipidaemia and hyperuricaemia in the community aged over 65 in Pudong New Area show an upward dynamic change. These results suggeste that early intervention and health education for hypertension and abnormal glucose and lipid metabolism should be carried out in community elderly. -
Key words:
- The aged /
- Healthy examination /
- Hypertension /
- Diabetes /
- Hyperuricaemia
-
表 1 社区老年人BMI、血压及UA比较(x±s)
Table 1. Comparison of BMI, blood pressure and UA in community elderly (x±s)
年份 人数 BMI SBP(mm Hg) DBP(mm Hg) UA(μmol/L) 男性 女性 男性 女性 男性 女性 男性 女性 2014 2 846 25.3±2.5 24.8±2.6 130.5±11.4 132.1±10.8 74.6±9.7 75.3±9.4 329.9±47.4a 280.6±47.2 2019 2 846 26.9±2.9 25.3±2.8 141.2±13.2 144.2±16.8 78.9±9.1 80.4±8.6 366.5±61.3a 314.8±52.9 t值 0.587 0.612 3.125 2.994 0.437 0.396 2.357 2.569 P值 0.253 0.221 0.023 0.027 0.392 0.422 0.034 0.030 注:与女性相比,aP<0.05。 表 2 社区老年人GLU、HbA1c、LDL及TCH比较(x±s)
Table 2. Comparison of GLU, HbA1c, LDL and TCH in community elderly (x±s)
年份 人数 GLU(mmol/L) HbA1c(%) LDL(mmol/L) TCH(mmol/L) 男性 女性 男性 女性 男性 女性 男性 女性 2014 2 846 5.5±1.1 5.6±0.9 4.8±0.7 5.1±0.6 2.4±0.5 2.6±0.6 4.4±0.8 4.6±0.9 2019 2 846 6.6±1.3 6.8±1.4 5.6±0.9 5.8±0.8 3.1±0.7 3.2±0.8 5.1±0.9 5.2±1.0 t值 2.526 2.935 2.418 2.317 3.615 2.749 2.397 2.359 P值 0.025 0.021 0.032 0.038 0.019 0.022 0.033 0.036 表 3 社区老年人TG、Cr、ALT和AST比较(x±s)
Table 3. Comparison of TG, Cr, ALT and AST in community elderly (x±s)
年份 人数 TG(mmol/L) Cr(μmol/L) ALT(U/L) AST(U/L) 男性 女性 男性 女性 男性 女性 男性 女性 2014 2 846 1.5±0.4 1.6±0.5 77.2±8.4 73.7±7.1 23.8±6.1 25.9±6.5 24.6±7.4 28.7±7.4 2019 2 846 1.9±0.5 2.1±0.6 80.6±8.7 78.5±9.7 27.3±7.5 28.5±6.7 27.6±6.2 31.6±8.4 t值 2.355 3.145 0.412 0.454 0.578 0.498 0.596 0.486 P值 0.031 0.028 0.383 0.362 0.295 0.312 0.286 0.342 表 4 社区老年人不同年份高血压、糖尿病及高脂血症检出率比较[人(%)]
Table 4. Comparison of the detection rates of hypertension, diabetes and hyperlipidemia in community elderly in different years [cases(%)]
年份 人数 高血压 糖尿病 高甘油三酯 高胆固醇 2014 2 846 643(22.6) 516(18.1) 429(15.1) 424(14.9) 2019 2 846 942(33.1) 805(28.3) 689(24.2) 677(23.8) χ2值 77.650 81.765 74.667 71.511 P值 < 0.001 < 0.001 < 0.001 < 0.001 表 5 社区老年人不同年份高尿酸血症、脂肪肝、肝肾功能异常检出率比较[人(%)]
Table 5. Comparison of the detection rates of hyperuricemia, fatty liver and abnormal liver and kidney function in community elderly in different years [cases(%)]
年份 人数 高尿酸血症 脂肪肝 肝功能异常 肾功能异常 2014 2 846 546(19.2) 307(10.8) 99(3.5) 131(4.6) 2019 2 846 808(28.4) 344(12.1) 111(3.9) 145(5.1) χ2值 66.014 2.248 0.598 0.644 P值 < 0.001 0.134 0.439 0.422 -
[1] 庄洁, 张旭东, 李伟, 等. 老年常见慢性病共病患者社区健康管理需求[J]. 中国老年学杂志, 2021, 41(10): 2179-2183. doi: 10.3969/j.issn.1005-9202.2021.10.046ZHUANG J, ZHANG X D, LI W, et al. Community health management needs of elderly patients with common chronic diseases[J]. Chinese Journal of Gerontology, 2021, 41(10): 2179-2183. doi: 10.3969/j.issn.1005-9202.2021.10.046 [2] OLIVEROS E, PATEL H, KYUNG S, et al. Hypertension in older adults: Assessment, management, and challenges[J]. Clin Cardiol, 2020, 43(2): 99-107. doi: 10.1002/clc.23303 [3] WINOCOUR P H. Diabetes and chronic kidney disease: An increasingly common multi-morbid disease in need of a paradigm shift in care[J]. Diabet Med, 2018, 35(3): 300-305. doi: 10.1111/dme.13564 [4] GUO L X, ZHENG J, PAN Q, et al. Changes in direct medical cost and medications for managing diabetes in Beijing, China, 2016 to 2018: Electronic insurance data analysis[J]. Ann Fam Med, 2021, 19(4): 332-341. doi: 10.1370/afm.2686 [5] 《中国高血压防治指南》修订委员会. 中国高血压防治指南2018年修订版[J]. 心脑血管病防治, 2019, 19(1): 1-44. doi: 10.3969/j.issn.1009-816X.2019.01.001Revision committee of the Chinese guidelines for the management of hypertension. 2018 Chinese guidelines for the management of hypertension[J]. Cardio-cerebrovascular Disease Prevention and Treatment, 2019, 19(1): 1-44. doi: 10.3969/j.issn.1009-816X.2019.01.001 [6] 中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2017年版)[J]. 中华糖尿病杂志, 2018, 10(1): 4-67. doi: 10.3760/cma.j.issn.1674-5809.2018.01.003Diabetes Society of Chinese Medical Association. Guidelines for the prevention and control of type 2 diabetes in China (2017 Edition)[J]. Chinese Journal of Diabetes, 2018, 10(1): 4-67. doi: 10.3760/cma.j.issn.1674-5809.2018.01.003 [7] 中国成人血脂异常防治指南修订联合委员会. 中国成人血脂异常防治指南(2016年修订版)[J]. 中国循环杂志, 2016, 31(10): 937-953. doi: 10.3969/j.issn.1000-3614.2016.10.001Joint Committee on the revision of guidelines for the prevention and treatment of dyslipidemia in adults in China. Guidelines of the prevention and treatment for dyslipidemia in Chinese adults (2016 Edition)[J]. Chinese Circulation Journal, 2016, 31(10): 937-953. doi: 10.3969/j.issn.1000-3614.2016.10.001 [8] 中华医学会肝病学分会脂肪肝和酒精性肝病学组, 中国医师协会脂肪性肝病专家委员会. 非酒精性脂肪性肝病防治指南(2018更新版)[J]. 中华肝脏病杂志, 2018, 26(3): 195-203. doi: 10.3760/cma.j.issn.1007-3418.2018.03.008Fatty liver and alcoholic liver disease group of Hepatology branch of Chinese Medical Association, fatty liver disease expert committee of Chinese Medical Association. Guidelines of the prevention and treatment for nonalcoholic fatty liver disease: A 2018 update[J]. Chinese Journal of Hepatology, 2018, 26(3): 195-203. doi: 10.3760/cma.j.issn.1007-3418.2018.03.008 [9] 王丽敏, 陈志华, 张梅, 等. 中国老年人群慢性病患病状况和疾病负担研究[J]. 中华流行病学杂志, 2019, 40(3): 277-283.WANG L M, CHEN Z H, ZHANG M, et al. Study on the prevalence and burden of chronic diseases in the elderly population in China[J]. Chinese Journal of Epidemiology, 2019(3): 277-283. [10] 王姣锋, 张紫欢, 崔月, 等. 上海部分社区老年人共病患病模式及其影响因素分析[J]. 老年医学与保健, 2017, 23(2): 97-101. doi: 10.3969/j.issn.1008-8296.2017.02.011WANG J F, ZHANG Z H, CUI Y, et al. Analysis of comorbidity patterns and influencing factors among the elderly in some communities in Shanghai[J]. Geriatrics and Health Care, 2017, 23(2): 97-101. doi: 10.3969/j.issn.1008-8296.2017.02.011 [11] 朱仁敏, 赵慧华, 左丹妮. 上海市医联体模式下老年共病患者健康管理体验的质性研究[J]. 护士进修杂志, 2021, 36(21): 2007-2011. https://www.cnki.com.cn/Article/CJFDTOTAL-FSJX202121021.htmZHU R M, ZHAO H H, ZUO D N, et al. A qualitative study on the health management experience of elderly comorbidity patients under the mode of Medical Association in Shanghai[J]. Journal of Nurses Training, 2021, 36(21): 2007-2011. https://www.cnki.com.cn/Article/CJFDTOTAL-FSJX202121021.htm [12] 罗瑶, 邓学学, 徐晓茹, 等. 基于大数据老年多重慢性病风险预测模型构建探究[J]. 中华全科医学, 2021, 19(12): 1979-1982. doi: 10.16766/j.cnki.issn.1674-4152.002216LUO Y, DENG X X, XU X R, et al. Research on the construction of multi chronic disease risk prediction model for the elderly based on big data[J]. Chinese Journal of General Practice, 2021, 19(12): 1979-1982. doi: 10.16766/j.cnki.issn.1674-4152.002216 [13] 徐英, 郭艳芳, 刘峥, 等. 慢性病患者社区健康管理服务利用情况及影响因素研究[J]. 中国全科医学, 2022, 25(1): 55-61. https://www.cnki.com.cn/Article/CJFDTOTAL-QKYX202201006.htmXU Y, GUO Y F, LIU Z, et al. Study on the utilization and influencing factors of community health management services for patients with chronic diseases[J]. Chinese Journal of General Practice, 2022, 25(1): 55-61. https://www.cnki.com.cn/Article/CJFDTOTAL-QKYX202201006.htm [14] 李俊, 许东晴. 上海市朱泾社区65岁及以上老年人BMI、高血压、高血糖、高脂血症流行现状及关系分析[J]. 健康教育与健康促进, 2019, 14(1): 41-43, 47. https://www.cnki.com.cn/Article/CJFDTOTAL-JYCJ201901015.htmLI J, XU D Q. Epidemiological status and relationship analysis of BMI, hypertension, hyperglycemia and hyperlipidemia among the elderly aged 65 and above in Zhujing community, Shanghai[J]. Health Education and Health Promotion, 2019, 14(1): 41-43, 47. https://www.cnki.com.cn/Article/CJFDTOTAL-JYCJ201901015.htm [15] 李静, 折剑青, 罗娟娟, 等. 老年高血压患者血压昼夜节律与颈动脉粥样硬化的相关性研究[J]. 中华全科医学, 2021, 19(4): 534-537. doi: 10.16766/j.cnki.issn.1674-4152.001854LI J, ZHE J Q, LUO J J, et al. Relationship between circadian rhythm of blood pressure and carotid atherosclerosis in elderly patients with hypertension[J]. Chinese Journal of General Practice, 2021, 19(4): 534-537. doi: 10.16766/j.cnki.issn.1674-4152.001854 [16] 刘瑶霞, 田慧, 陈平, 等. 中国老年糖尿病患者血尿酸现况调查(GDCR研究基线4)[J]. 中国糖尿病杂志, 2019, 27(8): 561-566. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGTL201908001.htmLIU Y X, TIAN H, CHEN P, et al. Survey of serum uric acid in elderly patients with diabetes in China (GDCR study baseline 4)[J]. Chinese Journal of Diabetes, 2019, 27(8): 561-566. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGTL201908001.htm [17] 翁雪燕, 陈绵雄, 张菊云. 老年糖尿病患者游离脂肪酸水平与高尿酸血症的相关性[J]. 中国老年学杂志, 2020, 40(22): 4731-4733. https://www.cnki.com.cn/Article/CJFDTOTAL-ZLXZ202022009.htmWENG X Y, CHEN M X, ZHANG J Y. Correlation between free fatty acid level and hyperuricemia in elderly patients with diabetes[J]. Chinese Journal of Gerontology, 2020, 40(22): 4731-4733. https://www.cnki.com.cn/Article/CJFDTOTAL-ZLXZ202022009.htm [18] 诸国华, 丁存涛, 孙希鹏, 等. 老年高血压患者血清尿酸水平与代谢综合征的相关性研究[J]. 中华老年心脑血管病杂志, 2018, 20(11): 1124-1128. https://www.cnki.com.cn/Article/CJFDTOTAL-LNXG201811002.htmZHU G H, DING C T, SUN X P, et al. Study on the correlation between serum uric acid level and metabolic syndrome in elderly patients with hypertension[J]. Chinese Journal of Geriatric Heart Brain and Vessel Diseases, 2018, 20(11): 1124-1128. https://www.cnki.com.cn/Article/CJFDTOTAL-LNXG201811002.htm [19] FRAGOPOULOU E, CHOLEVA M, ANTONOPOULOU S, et al. Wine and its metabolic effects. A comprehensive review of clinical trials[J]. Metabolism, 2018, 83: 102-119. [20] LI Z, HU Y, YAN R N, et al. Twenty minute moderate-intensity post-dinner exercise reduces the postprandial glucose response in Chinese patients with type 2 diabetes[J]. Med Sci Monit, 2018, 24: 7170-7177.
计量
- 文章访问数: 362
- HTML全文浏览量: 123
- PDF下载量: 14
- 被引次数: 0