Effect of reducing paracentric defocusing soft lens on myopia in children and its effect on diopter and axial length
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摘要:
目的 探讨减少旁中心离焦软镜治疗儿童近视的临床效果，分析其对患儿屈光度、眼轴长度的影响。 方法 选择2020年1月—2021年6月宁波市眼科医院诊治的100例近视患儿，按照完全随机数字表法分成对照组和观察组，对照组50例采用普通框架眼镜治疗，观察组50例采用减少旁中心离焦软镜治疗。观察2组患儿的屈光度、眼轴长度、裸眼视力、视觉质量、临床疗效及不良反应。 结果 治疗后，观察组患儿的屈光度[(-2.23±0.51)D]低于对照组[(-3.06±0.62)D, P＜0.05]；观察组患儿的眼轴长度[(24.14±0.38)mm]小于对照组[(26.01±0.55)mm, P＜0.05]；观察组患儿的裸眼视力(1.03±0.18)高于对照组(0.82±0.13, P＜0.05)；观察组患儿的客观散射指数(0.67±0.11)小于对照组(0.81±0.14, P＜0.05)，调制传递函数、斯特列尔比(37.81±5.20、0.49±0.05)大于对照组(32.97±4.88、0.42±0.07，均P＜0.05)；观察组总有效率为92.0%(46/50)，高于对照组的74.0%(37/50, P＜0.05)；观察组不良反应发生率为6.0%(3/50)，与对照组的10.0%(5/50)相近(P＞0.05)。 结论 减少旁中心离焦软镜治疗儿童近视效果较好，可改善患儿的屈光度、眼轴长度、裸眼视力、视觉质量，不良反应少，值得应用。 Abstract:Objective To explore the clinical effect of reducing paracentral defocusing soft lens on myopia in children, and analyze its influence on diopter and axial length in children. Methods A total of 100 children with myopia who were admitted to Optometry Clinic of Ningbo Eye Hospital from January 2020 to June 2021 were divided into control group and observation group by random humber table. There were 50 cases in the control group treated with ordinary frame glasses, and 50 cases in the observation group were treated with reduced paracentric defocusing soft lens. The diopter, axial length, naked eye vision, visual quality, clinical efficacy and adverse reactions were observed. Results After treatment, the diopter of the observation group [(-2.23±0.51) D] was lower than that of the control group [(-3.06±0.62) D, P < 0.05]; the axial length in the observation group [(24.14±0.38) mm] was shorter than that in the control group [(26.01±0.55) mm, P < 0.05]; the naked eye visual acuity of the observation group (1.03±0.18) was higher than that of the control group (0.82±0.13, P < 0.05); the objective scattering index of the observation group (0.67±0.11) was lower than that of the control group (0.81±0.14, P < 0.05); and the modulation transfer function and Strehl ratio of the observation group (37.81±5.20, 0.49±0.05) were higher than those of the control group (32.97±4.88, 0.42±0.07, all P < 0.05). The total effective rate of the observation group was 92.0% (46/50), which was higher than that of the control group [74.0% (37/50), P < 0.05]. The incidence of adverse reactions in the observation group was 6.0% (3/50), which was close to 10.0% (5/50) in the control group (P>0.05). Conclusion Reducing paracentric defocusing soft lens is effective in the treatment of myopia in children. It can improve the diopter, axial length, naked eye vision and visual quality of children with fewer adverse reactions, and it is worthy of application. -
表 1 2组近视患儿治疗前后屈光度比较(x±s，D)
Table 1. Diopter comparison of two groups of myopia children before and after treatment (x±s, D)
组别 例数 治疗前 治疗后 对照组 50 -1.81±0.46 -3.06±0.62 观察组 50 -1.83±0.43 -2.23±0.51 t值 0.225 7.311 P值 0.823 ＜0.001 
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表 2 2组近视患儿治疗前后眼轴长度比较(x±s，mm)
Table 2. Comparison of axial length of two groups of myopic children before and after treatment (x±s, mm)
组别 例数 治疗前 治疗后 对照组 50 24.25±0.47 26.01±0.55 观察组 50 24.29±0.50 24.14±0.38 t值 0.412 19.780 P值 0.681 ＜0.001
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表 3 2组近视患儿治疗前后裸眼视力比较(x±s)
Table 3. Comparison of naked eye visual acuity of children with myopia in 2 groups before and after treatment (x±s)
组别 例数 治疗前 治疗后 对照组 50 0.45±0.16 0.82±0.13 观察组 50 0.43±0.15 1.03±0.18 t值 0.645 6.688 P值 0.521 ＜0.001
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表 4 2组近视患儿治疗前后视觉质量比较(x±s)
Table 4. Comparison of visual quality of two groups of children with myopia before and after treatment (x±s)
组别 例数 客观散射指数 调制传递函数 斯特列尔比 治疗前 治疗后 治疗前 治疗后 治疗前 治疗后 对照组 50 1.12±0.20 0.81±0.14 28.45±3.63 32.97±4.88 0.35±0.04 0.42±0.07 观察组 50 1.14±0.18 0.67±0.11 28.41±3.66 37.81±5.20 0.34±0.06 0.49±0.05 t值 0.526 5.560 0.055 4.799 0.981 5.754 P值 0.600 ＜0.001 0.956 ＜0.001 0.330 ＜0.001
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