新生儿单纯疱疹病毒Ⅰ型重症肺炎1例并文献复习

曹芳; 叶同生; 冯广彬; 华山; 王昶

doi:10.16766/j.cnki.issn.1674-4152.002881

新生儿单纯疱疹病毒Ⅰ型重症肺炎1例并文献复习

doi: 10.16766/j.cnki.issn.1674-4152.002881

曹芳^1, ,,
叶同生²,
冯广彬³,
华山¹,
王昶⁴

1.
复旦大学附属儿科医院安徽医院安徽省儿童医院呼吸科，安徽合肥 233000
2.
复旦大学附属儿科医院安徽医院安徽省儿童医院新生儿科，安徽合肥 233000
3.
阜阳市颍上县人民医院儿科，安徽阜阳 236200
4.
复旦大学附属儿科医院安徽医院安徽省儿童医院影像中心，安徽合肥 233000

详细信息

通讯作者:
曹芳，E-mail：1257744248@qq.com

中图分类号: R722.1 R373.11
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- 被引次数: 0
出版历程
- 收稿日期: 2022-02-15
- 网络出版日期: 2023-04-20

A case of neonatal herpes simplex virus type Ⅰ severe pneumonia and literature review

1.
Department of Respiratory Medicine, Anhui Children's Hospital, Pediatric Hospital Affiliated to Fudan University, Hefei, Anhui 233000, China

摘要

摘要: 本文报告单纯疱疹病毒(herpes simplex virus，HSV)Ⅰ型感染新生儿重症肺炎1例并文献复习。该新生儿以“气促、口吐泡沫、呛奶”呼吸系统表现为主，肺部CT提示双肺呈广泛弥漫性网格影改变，临床较少见，经及时诊断及给予更昔洛韦静滴联合干扰素雾化抗病毒及支持治疗，患儿恢复良好，出院随访1年，生长发育正常。
- 新生儿 /
- 单纯疱疹病毒 /
- 重症肺炎 /
- 宏基因 /
- α干扰素
Abstract: A case of severe neonatal pneumonia infected by herpes simplex virus (HSV) type Ⅰ was reported and the literature was reviewed. The respiratory system of the neonate was mainly manifested as "shortness of breath, foaming at the mouth, and choking milk". The Lung CT indicated that both lungs presented widespread diffuse grid changes, which was rare in clinic. After timely diagnosis and ganciclovir intravenous drops combined with interferon atomization antiviral and supportive treatment, the child recovered well, and was discharged with normal growth and development at 1 year follow-up.
- Neonatal /
- Herpes simplex virus /
- Severe pneumonia /
- Metagenome /
- α interferon

HTML全文

图 1 住院期间肺部CT影像

注：A为4月5日检查；B为4月11日检查；C为4月22日检查；D为5月22日检查。两肺呈弥漫性间质性改变。

Figure 1. Pulmonary CT imaging during hospitalization

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图 2 出院后随访胸部CT影像

注：A为6月18日检查，B为8月3日检查。两下肺仍然呈弥漫性间质性改变。

Figure 2. Follow up chest CT imaging after discharge

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参考文献(16)

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