良性发作性位置性眩晕患者手法复位后复发的影响因素分析

刘斌; 许笑天; 符雪涛; 王英歌; 刘雨霏; 唐铁钰

doi:10.16766/j.cnki.issn.1674-4152.003449

良性发作性位置性眩晕患者手法复位后复发的影响因素分析

doi: 10.16766/j.cnki.issn.1674-4152.003449

1.
扬州大学附属医院神经内科，江苏扬州 225001
2.
扬州大学附属医院康复医学科

基金项目:

国家自然科学基金项目 81901084

详细信息

通讯作者:
唐铁钰，E-mail：ydfytty@163.com

中图分类号: R764.3 R441.2
计量
- 文章访问数: 55
- HTML全文浏览量: 21
- PDF下载量: 8
- 被引次数: 0
出版历程
- 收稿日期: 2023-10-19
- 网络出版日期: 2024-05-29

Analysis of factors affecting recurrence in patients with benign paroxysmal positional vertigo after manual repositioning

1.
Department of Neurology, Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu 225001, China

摘要

摘要: 目的通过分析良性发作性位置性眩晕(BPPV)患者手法复位后相关影响因素，探讨可能导致BPPV复发的潜在危险因素，为降低再发率提供理论基础。方法选取2020年1月—2021年12月于扬州大学附属医院神经内科门诊确诊BPPV并治愈的170例患者。随访2年，根据是否复发分为复发组(70例)和未复发组(100例)。统计患者资料并通过logistic回归分析研究复发的危险因素。结果 70例复发患者中，复发1次39例，复发2次27例，复发3次及以上的患者4例。Logistic回归分析显示女性(OR=11.623, 95% CI: 4.104~20.634, P < 0.001)、焦虑(OR=4.200, 95% CI: 1.186~14.873, P=0.026)、疲劳(OR=5.025, 95% CI: 1.771~14.255, P=0.002)、睡眠障碍(OR=4.080, 95% CI: 1.152~14.447, P=0.002)、外伤(OR=4.802, 95% CI: 1.692~13.622, P=0.023)以及合并高血压(OR=4.938, 95% CI: 1.740~14.009, P < 0.001)均是BPPV患者复发的危险因素，糖尿病、家族史和吸烟史与是否复发之间无明显相关性。结论性别、焦虑、疲劳、睡眠障碍、外伤以及合并高血压是BPPV患者复发的影响因素，可以更有针对性地对BPPV复发的管理和预防提供参考。
- 良性发作性位置性眩晕 /
- 手法复位 /
- 复发 /
- 影响因素
Abstract: Objective This study aims to analyze the factors influencing the recurrence of benign paroxysmal positional vertigo (BPPV) following manual repositioning, revealing potential risk factors for BPPV recurrence, and providing a theoretical basis for reducing the recurrence rate. Methods A total of 170 patients diagnosed with and cured for BPPV at the Neurology Department of Affiliated Hospital of Yangzhou University between January 2020 and December 2021 were selected in this study. A 2-year follow-up was conducted, and the patients were divided into the recurrence group (n=70) and non-recurrence group (n=100) based on recurrence status. Patient data were collected and logistic regression analysis was performed to identify risk factors associated with BPPV recurrence. Results Among the 70 recurrent patients, 39 experienced a single recurrence, while 27 encountered two recurrences, and 4 had three or more recurrences. Logistic regression analysis showed that female (OR=11.623, 95% CI: 4.104-20.634, P < 0.001), anxiety (OR=4.200, 95% CI: 1.186-14.873, P=0.026), fatigue (OR=5.025, 95% CI: 1.771-14.255, P=0.002), sleep disorder (OR=4.080, 95% CI: 1.152-14.447, P=0.002), trauma (OR=4.802, 95% CI: 1.692-13.622, P=0.023) and comorbid hypertension (OR=4.938, 95% CI: 1.740-14.009, P < 0.001) were risk factors for recurrence in BPPV patients, and diabetes, family history and smoking history were not significantly correlated with the presence or absence of recurrence. Conclusion Gender, anxiety, fatigue, sleep disorders, trauma, and hypertension were the influencing factors contributing to the recurrence of BPPV. These findings offer more targeted insights for the management and prevention of BPPV recurrence.
- Benign paroxysmal positional vertigo /
- Manual reduction /
- Recurrence /
- Influencing factors

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表 1 2组BPPV患者人口学及临床资料比较

Table 1. Comparison of demographic and clinical data of BPPV patients in 2 two groups

组别	例数	年龄 (x±s，岁)	性别[例(%)]		高血压 [例(%)]	睡眠障碍 [例(%)]	疲劳 [例(%)]	糖尿病 [例(%)]	家族史 [例(%)]	吸烟史 [例(%)]	外伤史 [例(%)]	焦虑 [例(%)]
组别	例数	年龄 (x±s，岁)	女性	男性	高血压 [例(%)]	睡眠障碍 [例(%)]	疲劳 [例(%)]	糖尿病 [例(%)]	家族史 [例(%)]	吸烟史 [例(%)]	外伤史 [例(%)]	焦虑 [例(%)]
复发组	70	49.63±8.94	61(87.14)	9(12.86)	45(64.29)	43(61.43)	25(35.71)	21(30.00)	26(37.14)	23(32.86)	17(24.29)	18(25.71)
未复发组	100	48.55±9.56	51(51.00)	49(49.00)	24(24.00)	34(34.00)	16(16.00)	16(16.00)	19(19.00)	13(13.00)	4(4.00)	10(10.00)
统计量		0.752^a	23.930^b		27.713^b	12.502^b	8.745^b	4.740^b	6.963^b	9.727^b	15.650^b	7.391^b
P值		0.458	<0.001		<0.001	<0.001	0.003	0.030	0.008	0.002	<0.001	0.007
注：^a为t值，^b为χ²值。

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表 2 变量赋值情况

Table 2. Variable assignment

变量	赋值方法
复发	否=0，是=1
性别	男性=0，女性=1
焦虑	无=0，有=1
糖尿病	无=0，有=1
家族史	无=0，有=1
吸烟史	无=0，有=1
疲劳	无=0，有=1
睡眠障碍	否=0，是=1
外伤	否=0，是=1
高血压	否=0，是=1

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表 3 BPPV再发患者影响因素logistic回归分析

Table 3. Logistic regression analysis of influencing factors of patients with BPPV recurrence

变量	B	SE	Waldχ²	P值	OR值	95% CI
女性	2.453	0.587	17.445	<0.001	11.623	4.104~20.634
焦虑	1.435	0.645	4.949	0.026	4.200	1.186~14.873
糖尿病	0.144	0.498	0.083	0.773	1.155	0.435~3.066
家族史	0.885	0.492	3.241	0.072	2.423	0.924~6.349
吸烟史	0.613	0.613	1.349	0.245	1.846	0.656~5.192
疲劳	1.614	0.532	9.209	0.002	5.025	1.771~14.255
睡眠障碍	1.406	0.454	9.573	0.002	4.080	1.152~14.447
外伤	1.569	0.688	5.195	0.023	4.802	1.692~13.622
高血压	1.597	0.442	13.032	<0.001	4.938	1.740~14.009

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