The mediating effect of hope level between posttraumatic growth and quality of life in patients with lung cancer after thoracoscopic surgery
-
摘要:
目的 分析肺癌患者胸腔镜手术创伤后成长和生活质量的影响因素及希望水平在其中的中介效应。 方法 选择2021年1月—2022年12月间宜兴市人民医院收治的350例接受胸腔镜手术治疗的肺癌患者作为研究对象。采用世界卫生组织生存质量评估简表对患者的生活质量进行评估；采用创伤后成长量表对患者的创伤后成长情况进行评估；采用Herth希望量表(HHI)对患者的希望水平进行评估，根据HHI评分将患者分为希望低水平组(89例)、中水平组(132例)和高水平组(129例)。通过Spearman相关性检验分析肺癌胸腔镜术后患者希望水平与创伤后成长和生活质量之间的关系，并分析希望水平在肺癌患者胸腔镜手术创伤后成长和生活质量之间的中介效应。 结果 希望水平低、中、高3组患者的生活质量总分分别为(80.32±6.54)分、(86.87±7.59)分、(94.88±8.94)分，差异有统计学意义(F=4.872, P=0.008)。希望水平低、中、高3组患者的创伤后成长总分分别为(66.51±8.43)分、(75.64±7.28)分、(87.45±7.15)分，差异有统计学意义(F=4.814, P=0.009)。希望水平在创伤后成长和生活质量间起部分中介效应，其中介效应占比为46.39%(0.374×0.351/0.283×100%)。 结论 希望水平在肺癌患者胸腔镜术后创伤后成长和生活质量间起到重要的中介效应，临床上可通过改善患者希望水平提高患者生活质量和术后创伤后成长。 Abstract:Objective To analyze the influencing factors of posttraumatic growth and quality of life of lung cancer patients after thoracoscopic surgery, and the mediating effect of hope level in the traumatic process. Methods A total of 350 lung cancer patients who underwent thoracoscopic surgery at Yixing People's Hospital between January 2021 and December 2022 were selected as the study subjects. The World Health Organization Quality of Life-BREF was used to assess the patients' quality of life. The posttraumatic growth inventory was employed to evaluate the patients' posttraumatic growth. The Herth hope index was used to measure the patients' level of hope. The patients were divided into hope low level group (89 cases), hope medium level group (132 cases) and hope high level group (129 cases) according to the HHI score. Spearman's correlation test was performed to analyze the relationship between hope levels and posttraumatic growth and quality of life in lung cancer patients after thoracoscopic surgery. Furthermore, the mediating effect of hope levels on the relationship between posttraumatic growth and quality of life in these patients was examined. Results The overall quality of life scores for patients with low, medium, and high levels of hope were 80.32±6.54, 86.87±7.59, and 94.88±8.94, respectively, with statistically significant differences (F=4.872, P=0.008). The total posttraumatic growth scores for patients with low, medium, and high levels of hope were 66.51±8.43, 75.64±7.28, and 87.45±7.15, respectively, showing significant differences (F=4.814, P=0.009). Hope levels partially mediated the relationship between posttraumatic growth and quality of life, with a mediation effect ratio of 46.39% (0.374×0.351/0.283×100%). Conclusion Hope level plays an important mediating effect between posttraumatic growth and quality of life in patients with lung cancer after thoracoscopic surgery. Improving hope level can improve patients' quality of life and posttraumatic growth in clinical practice. -
表 1 不同希望水平肺癌患者一般资料比较
Table 1. Comparison of general data of lung cancer patients with different levels of hope
组别 例数 性别(例) 年龄(x±s，岁) 受教育年限(x±s，年) 男性 女性 低水平组 89 46 43 57.48±6.12 6.86±4.38 中水平组 132 74 58 57.57±7.23 7.01±3.29 高水平组 129 72 57 57.42±8.01 6.93±3.74 统计量 0.486a 0.174b 0.172b P值 0.784 0.840 0.865 注：a为χ2值，b为F值。 
下载: 导出CSV
表 2 不同希望水平肺癌患者生活质量评分比较(x±s，分)
Table 2. Comparison of quality of life scores among lung cancer patients with varying levels of hope(x±s, points)
组别 例数 心理 生理 环境 社会关系 总分 低水平组 89 19.83±1.02 21.02±0.98 20.84±1.04 18.63±1.21 80.32±6.54 中水平组 132 21.93±1.11 22.74±1.21 21.79±1.15 20.41±1.16 86.87±7.59 高水平组 129 23.57±1.23 24.01±1.15 23.85±1.07 23.45±1.08 94.88±8.94 F值 4.854 4.192 5.012 4.493 4.872 P值 0.008 0.016 0.007 0.012 0.008
下载: 导出CSV
表 3 不同希望水平肺癌患者创伤后成长评估比较(x±s，分)
Table 3. Assessment results of post-traumatic growth in lung cancer patients with different levels of hope(x±s, points)
组别 例数 个人力量 新的可能性 与他人关系 欣赏生活 精神改变 总分 低水平组 89 12.32±1.83 10.93±1.83 20.03±1.21 12.21±1.74 11.02±1.08 66.51±8.43 中水平组 132 14.12±1.21 12.07±1.26 22.19±1.19 13.98±1.63 13.28±1.16 75.64±7.28 高水平组 129 16.94±1.39 15.02±1.47 24.38±1.07 15.34±1.63 15.77±1.21 87.45±7.15 F值 4.395 3.994 4.183 4.374 4.732 4.814 P值 0.014 0.019 0.016 0.013 0.009 0.009
下载: 导出CSV
表 4 希望水平与术后创伤后成长和生活质量间的关系
Table 4. Relationship between levels of hope, post-traumatic growth, and quality of life
指标 r值 P值 生活质量 心理 0.754 <0.001 生理 0.699 <0.001 环境 0.739 <0.001 社会关系 0.684 <0.001 术后创伤后成长 个人力量 0.722 <0.001 新的可能性 0.719 <0.001 与他人关系 0.765 <0.001 欣赏生活 0.804 <0.001 精神改变 0.811 <0.001
下载: 导出CSV
-
[1] CHIH S, MCDONALD M, DIPCHAND A, et al. Canadian Cardiovascular Society/Canadian Cardiac Transplant Network position statement on heart transplantation: patient eligibility, selection, and post-transplantation care[J]. Can J Cardiol, 2020, 36(3): 335-356. doi: 10.1016/j.cjca.2019.12.025 [2] BONILLA C, ZURITA M. Cell-based therapies for traumatic brain injury: therapeutic treatments and clinical trials[J]. Biomedicines, 2021, 9(6): 669. doi: 10.3390/biomedicines9060669 [3] WHITE A J, GILAD R, MOTIVALA S, et al. NPWT[J]. Bioengineering, 2022, 9(11): 614. doi: 10.3390/bioengineering9110614 [4] VAN DER HAGE J, SANDRUCCI S, AUDISIO R, et al. The ESSO core curriculum committee update on surgical oncology[J]. Eur J Surg Oncol, 2021, 47(11): e1-e30. doi: 10.1016/j.ejso.2021.10.003 [5] KLOTZ R, LARMANN J, KLOSE C, et al. Usage and demands for complementary medicine in orthopaedic and trauma patients (Abstract ID: 178)[J]. Eur Surg Res, 2020, 61(1): 1-49. doi: 10.1159/000510948 [6] 刘怡均, 林向英, 张燕. 中文版世界卫生组织生存质量测定量表简表用于终末期肾病的信效度验证[J]. 首都医科大学学报, 2021, 42(4): 635-641.LIU Y J, LIN X Y, ZHANG Y. Validity and reliability of the Chinese version of World Health Organization Quality of Life-BREF among patients with end-stage renal disease[J]. Journal of Capital Medical University, 2021, 42(4): 635-641. [7] 董璐, 胡雁, 徐国会, 等. 中文版创伤后成长量表应用于乳腺癌患者的信效度分析[J]. 护理学杂志: 外科版, 2013, 28(22): 21-23.DONG L, HU Y, XU G H, et al. Reliability and validity of the Chinese version of post-traumatic growth inventory scale in breast cancer survivors[J]. Journal of Nursing Science, 2013, 28(22): 21-23. [8] 金晶, 尹碧, 陆佳玉, 等. PRECEDE模式联合急救干预对急性心肌梗死患者Herth希望量表评分、舒适度评分及SCL-90评分的影响[J]. 中国急救复苏与灾害医学杂志, 2020, 15(7): 780-783.JIN J, YIN B, LU J Y, et al. PRECEDE mode combined with emergency intervention on the effect of PR ECEDE nursing mode on the Herth expectation scale score, comfort score and scl-90 score of patients with acute myocardial infarction[J]. China Journal of Emergency Resuscitation and Disaster Medicine, 2020, 15(7): 780-783. [9] CASALI M, LAURI C, ALTINI C, et al. State of the art of 18F-FDG PET/CT application in inflammation and infection: a guide for image acquisition and interpretation[J]. Clin Transl, 2021, 9(4): 299-339. [10] GLARE P, OVERTON S, AUBREY K. Transition from acute to chronic pain: where cells, systems and society meet[J]. Pain Manag, 2020, 10(6): 421-436. doi: 10.2217/pmt-2019-0039 [11] RAGHU G, BERK M, CAMPOCHIARO P A, et al. The multifaceted therapeutic role of N-acetylcysteine (NAC) in disorders characterized by oxidative stress[J]. Curr Neuropharmacol, 2021, 19(8): 1202. [12] 脱广鑫, 闫沛静, 庞瑶, 等. 机器人辅助胸腔镜手术与传统胸腔镜手术在肺部良性病损切除术中的对比研究[J]. 中华胸心血管外科杂志, 2019, 35(6): 364-367.TUO G X, YAN P J, PANG Y, et al. The advantages of robot-assisted thoracoscopic surgery in the treatment of benign lung disease[J]. Chinese Journal of Thoracic and Cardiovascular Surgery, 2019, 35(6): 364-367. [13] NAJAFI-GHALEHLOU N, FEIZKHAH A, MOBAYEN M, et al. Plumping up a cushion of human biowaste in regenerative medicine: novel insights into a state-of-the-art reserve arsenal[J]. Stem Cell Rev Rep, 2022, 18(8): 2709-2739. doi: 10.1007/s12015-022-10383-3 [14] THOMAS A X, RIVIELLO JR J J, DAVILA-WILLIAMS D, et al. Pharmacologic and acute management of spinal cord injury in adults and children[J]. Curr Treat Option Ne, 2022, 24(7): 285-304. doi: 10.1007/s11940-022-00720-9 [15] SASSOON C R. Cystic fibrosis and the 15th national congress of cystic fibrosis Italian society[J]. Ital J Pediatr, 2020, 46(1): S1. doi: 10.1186/s13052-019-0764-1 [16] CIOSEK Ż, KOT K, KOSIK-BOGACKA D, et al. The effects of calcium, magnesium, phosphorus, fluoride, and lead on bone tissue[J]. Biomolecules, 2021, 11(4): 506. doi: 10.3390/biom11040506 [17] 刘叶, 王贤书, 王盛华, 等. 胸腔镜联合快速康复方案治疗儿童先天性膈疝[J]. 河北医药, 2023, 45(20): 3124-3127.LIU Y, WANG X S, WANG S H, et al. A combination treatment of thoracoscopy and enhanced recovery after surgery protocol in children with congenital diaphragmatic hernias[J]. Hebei Medical Journal, 2023, 45(20): 3124-3127. [18] DE WULF A, BLOEM C, CLARK T, et al. The sixth annual academic international medicine virtual congress and scientific forum, May 21-23, 2021: Best practices in shifting landscapes[J]. Int J Medical Sci, 2021, 7(4): 252. [19] KURNIAWATI E M, HASTOMO T, SANTOSO B, et al. Effect of amniotic membrane-derived mesenchymal stem cells on TNF-α expression and inflammatory cells infiltration during vesicovaginal fistule repair healing process[J]. Indian J Forensic Med Toxicol, 2020, 14(2): 1145-1149. [20] ANDERSEN B L, MCELROY J P, CARBONE D P, et al. Psychological symptom trajectories and non-small cell lung cancer survival: a joint model analysis[J]. Psychosom Med, 2022, 84(2): 215-223. doi: 10.1097/PSY.0000000000001027 [21] RIUDAVETS M, SULLIVAN I, ABDAYEM P, et al. Targeting HER2 in non-small-cell lung cancer (NSCLC): a glimpse of hope? An updated review on therapeutic strategies in NSCLC harbouring HER2 alterations[J]. ESMO Open, 2021, 6(5): 100260. DOI: 10.1016/j.esmoop.2021.100260. [22] TU M, WANG F, SHEN S, et al. Influences of psychological intervention on negative emotion, cancer-related fatigue and level of hope in lung cancer chemotherapy patients based on the PERMA framework[J]. Iran J Public Health, 2021, 50(4): 728. -
点击查看大图
表(4)
计量
- 文章访问数: 18
- HTML全文浏览量: 5
- PDF下载量: 2
- 被引次数: 0
