中西医治疗溃疡性结肠炎的比较与分析

许博洋; 杨雯迪; 李伟; 贾志春; 徐伟; 王嘉婉

doi:10.16766/j.cnki.issn.1674-4152.003701

中西医治疗溃疡性结肠炎的比较与分析

doi: 10.16766/j.cnki.issn.1674-4152.003701

1.
内蒙古自治区人民医院中西医结合科，内蒙古呼和浩特 010017
2.
内蒙古自治区监狱管理局第一医院急诊科，内蒙古呼和浩特 010050

基金项目:

内蒙古自治区自然科学基金面上项目 2023SHZR1708

内蒙古自治区健康科技计划项目 202201067

详细信息

通讯作者:
徐伟，E-mail：15147128678@163.com

中图分类号: R574.62 R256.3
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- 文章访问数: 35
- HTML全文浏览量: 21
- PDF下载量: 2
- 被引次数: 0
出版历程
- 收稿日期: 2024-02-12
- 网络出版日期: 2024-12-28

Comparison and analysis of traditional Chinese medicine and Western medicine in the treatment of ulcerative colitis

1.
Department of Integrative Medicine, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia 010017, China

摘要

摘要: 溃疡性结肠炎(ulcerative colitis，UC)作为常见的炎症性肠病(inflammatory bowel disease，IBD)，其发病机制目前尚未完全明确。多数学者认为，宿主遗传易感性和异常环境因素引起的宿主免疫与肠道微生物群关系的失衡，促进了UC患者肠道炎症的发生。在治疗上，西医通常运用氨基水杨酸、激素、免疫调节剂、生物制剂等药物。这些药物主要针对炎症反应和免疫调节发挥直接作用，能在短时间内显著改善症状，尤其在控制急性发作和重症UC方面成效显著。然而，这些药物普遍存在不同程度的副作用，且可能导致患者对药物产生依赖，从而加大停药后病情复发的风险。中医学认为UC是在素体脾胃虚弱的基础上，由于感受外邪、饮食失宜、情志失调等诱因而导致发病。在治疗上，中医在轻症及缓解期UC方面表现出显著的疗效。中医治疗不仅关注疾病本身，还高度重视患者的个体差异。通过辨证论治，为患者制定个性化的治疗方案。此外，中医治疗手段丰富多样，包括口服汤剂、中药灌肠、栓剂纳肛、针灸等。这些治疗方法在缓解症状的同时，有助于改善患者肠道功能、提高生活质量，且副作用较小，疗效持久。本文旨在通过中医病因病机、中医治疗、西医发病机制、西医治疗4个方面比较和分析中西医治疗UC的现状，以探索中西医结合治疗UC的可行性，为该病的诊治提供新思路、新方法。
- 溃疡性结肠炎 /
- 中医治疗 /
- 西医治疗 /
- 中西医结合
Abstract: Ulcerative colitis (UC), as a common inflammatory bowel disease (IBD), has an etiology that is not yet fully understood. Many scholars believe that an imbalance between host genetic susceptibility and abnormal environmental factors disrupted relationship between host immunity and intestinal microbiota, promoting the development of intestinal inflammation in UC patients. In treatment, Western medicine typically uses aminosalicylates, steroids, immunomodulators, and biological agents. These medications primarily target inflammatory responses and immune regulation, significantly improving symptoms in a short time, especially in controlling acute attacks and severe UC. However, these medications generally come with varying degrees of side effects and may lead to patient dependency, increasing the risk of relapse after discontinuation. Traditional Chinese medicine (TCM) views UC as a disease caused by external pathogens, improper diet, and emotional disturbances, all occurring against a backdrop of inherent spleen and stomach weakness. In treatment, TCM has shown significant efficacy in managing mild cases of UC and during remission stages. TCM treatment not only focuses on the disease itself but also pays great attention to individual differences among patients. Through syndrome differentiation, personalized treatment plans are formulated for each patient. Additionally, TCM offers a variety of treatment methods, including oral decoctions, herbal enemas, suppository anal administrations, and acupuncture. These treatments help alleviate symptoms, improve intestinal function, enhance quality of life, have fewer side effects, and provide lasting efficacy. This article aims to compare and analyze the current status of TCM and Western medicine in treating UC from four aspects: TCM etiology and pathogenesis, TCM treatment, Western medicine pathogenesis, and Western medicine treatment. It also explores the feasibility of integrating TCM and Western medicine in treating UC, providing new insights and methods for the diagnosis and treatment of this disease.
- Ulcerative colitis /
- Traditional Chinese medicine treatment /
- Western medicine treatment /
- Integration of traditional Chinese and western medicine

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