Clinical efficacy of single hole split endoscopy assisted by ultrasound bone knife in the treatment of calcified lumbar disc herniation
-
摘要:
目的 探讨钙化型腰椎间盘突出症(CLDH)采用超声骨刀辅助单孔分体内镜下椎间盘切除术(OSED)治疗的临床疗效,为临床提供参考。 方法 回顾性分析2022年1月—2023年2月在上海市浦东新区人民医院骨科治疗的25例CLDH患者资料,患者均应用超声骨刀辅助完成OSED。观察手术出血量、手术时间、术后下床时间、切口长度、术中透视次数及围手术期并发症等情况。比较患者术前、术后腰痛和腿痛VAS评分及Oswestry功能障碍指数(ODI);比较术前、术后3个月椎间盘CT横截面的钙化突出物面积;在末次随访时使用改良MacNab标准评估手术疗效。 结果 25例患者均手术顺利,未发生严重血管神经损伤的并发症。切口长度为(2.01±0.26)cm,手术用时为(87.40±12.84)min,手术出血量为(52.40±28.33)mL,术中透视次数为(2.88±1.01)次,术后下床时间为(22.56±7.80)h。患者术后各时间段腰痛、腿痛VAS评分及ODI指数较术前均明显下降(P<0.05)。与术前比较,术后3个月椎间盘CT横截面钙化物面积明显减小(P<0.001)。患者手术优良率达到92.0%(23/25)。 结论 应用超声骨刀辅助OSED治疗CLDH的疗效满意,具有创伤小、钙化突出物切除充分、并发症少等优势。 -
关键词:
- 单孔分体内镜 /
- 钙化型腰椎间盘突出症 /
- 超声骨刀 /
- 椎间盘切除术
Abstract:Objective To examine the clinical efficacy of ultrasonic osteotome-assisted one-hole split endoscopic discectomy (OSED) for calcified lumbar disc herniation (CLDH) and to provide a clinical reference point. Methods A retrospective analysis was conducted on 25 patients with CLDH who were treated at the Department of Orthopaedics in Shanghai Pudong New Area People's Hospital between January 2022 and February 2023. All patients underwent osteosynthesis with the assistance of an ultrasonic bone knife. It is crucial to meticulously observe and document the extent of surgical bleeding, the duration of the surgical procedure, the postoperative period required for patients to be able to get out of bed, the length of the incision, the frequency of intraoperative fluoroscopy, and any perioperative complications. A comparison of the visual analogue scale (VAS) and Oswestry disability Index (ODI) scores for low back pain and leg pain before and after surgery will be conducted. Furthermore, the area of calcified protrusions on the CT cross-section of intervertebral discs before and three months after surgery will be evaluated. Finally, the modified MacNab criteria will be employed to evaluate the surgical efficacy at the conclusion of the follow-up period. Results All 25 patients underwent surgical intervention without any significant complications, including vascular or nerve injury. The mean length of the incision was (2.01±0.26) cm, the mean surgical time was (87.40±12.84) min, the mean surgical bleeding volume was (52.40±28.33) mL, the mean frequency of intraoperative fluoroscopy was (2.88±1.01) times, and the mean postoperative time to get out of bed was (22.56±7.80) h. The VAS score and ODI index for lower back pain and leg pain in patients at different time points after surgery exhibited a statistically significant reduction compared to the pre-surgical period (P < 0.05). Moreover, the area of calcified material in the CT cross-section of the intervertebral disc demonstrated a significant reduction at the three-month post-surgical mark in comparison to the pre-surgical level (P < 0.001). The proportion of patients who were rated as excellent or good using the revised MacNab criteria was 92.0% (23/25). Conclusion The application of ultrasonic osteotome assisted OSED in the treatment of CLDH has satisfactory therapeutic effects, with advantages such as minimal trauma, sufficient removal of calcified protrusions, and fewer complications. -
表 1 25例单节段CLDH患者不同时间点腰腿痛VAS评分和ODI指数比较(x±s)
Table 1. Comparison of VAS scores for low back and leg pain, and ODI index at different time points in 25 patients with single-segment CLDH (x±s)
时间 腰痛VAS评分(分) 腿痛VAS评分(分) ODI指数(%) 术前 5.92±1.22 6.64±0.86 61.76±7.76 术后3 d 2.68±0.69a 2.40±0.58a 术后3个月 1.88±0.33ab 1.72±0.54ab 27.96±2.38a 术后12个月 1.00±0.50abc 1.08±0.49abc 14.80±2.71ac F值 154.630 240.545 412.905 P值 <0.001 <0.001 <0.001 注:与术前比较,aP<0.05;与术后3 d比较,bP<0.05,与术后3个月比较,cP<0.05。 -
[1] ZEHRA U, TRYFONIDOU M, IATRIDIS J C, et al. Mechanisms and clinical implications of intervertebral disc calcification[J]. Nat Rev Rheumatol, 2022, 18(6): 352-362. doi: 10.1038/s41584-022-00783-7 [2] KARAMOUZIAN S, ESKANDARY H, FARAMARZEE M, et al. Frequency of lumbar intervertebral disc calcification and angiogenesis, and their correlation with clinical, surgical, and magnetic resonance imaging findings[J]. Spine, 2010, 35(8): 881-886. doi: 10.1097/BRS.0b013e3181b9c986 [3] XU D B, CHEN Z Q, ZHAO Y C, et al. The clinical results of percutaneous endoscopic interlaminar discectomy (PEID) in the treatment of calcified lumbar disc herniation: a case-control study[J]. Pain physician, 2016, 19(2): 69-76. [4] WANG H, ZHOU T Y, GU Y T, et al. Evaluation of efficacy and safety of percutaneous transforaminal endoscopic surgery (PTES) for surgical treatment of calcified lumbar disc herniation: a retrospective cohort study of 101 patients[J]. BMC Musculoskelet Disord, 2021, 22(1): 65. DOI: 10.1186/s12891-020-03938-3. [5] 康鹏程, 杨静海, 陈良龙. 钙化型腰椎间盘突出症及其经皮内镜治疗进展[J]. 中国微创外科杂志, 2020, 20(5): 463-466, 470.KANG P C, YANG J H, CHEN L L. Calcification type and its recent advances in the treatment of percutaneous endoscopic lumbar disc prolapse[J]. Chinese Journal of Minimally Invasive Surgery, 2020, 20(5): 463-466, 470. [6] MILLER L, BHATTACHARYYA S, PRACYK J. Minimally invasive versus open transforaminal lumbar interbody fusion for single-level degenerative disease: a systematic review and meta-analysis of randomized controlled trials[J]. World Neurosurgery, 2020, 133: 358-365.e4. doi: 10.1016/j.wneu.2019.08.162 [7] 王辉, 陈雄生, 潘敏, 等. 单侧双通道内窥镜技术治疗单节段腰椎椎间盘突出症[J]. 脊柱外科杂志, 2023, 21(4): 254-258.WANG H, CHEN X S, PAN M, et al. Unilateral biportal endoscopic technique for single-segment lumbar disc herniation[J]. Journal of Spinal Surgery, 2023, 21(4): 254-258. [8] MACNAB I A N. Negative disc exploration: an analysis of the causes of nerve-root involvement in sixty-eight patients[J]. J Bone Joint Surg Am, 1971, 53(5): 891-903. doi: 10.2106/00004623-197153050-00004 [9] SHAO J, YU M, JIANG L, et al. Differences in calcification and osteogenic potential of herniated discs according to the severity of degeneration based on Pfirrmann grade: a cross-sectional study[J]. BMC Musculoskelet Disord, 2016, 17(1): 191. DOI: 10.1186/s12891-016-1015-x. [10] LORETO C, MUSUMECI G, CASTORINA A, et al. Degenerative disc disease of herniated intervertebral discs is associated with extracellular matrix remodeling, vimentin-positive cells and cell death[J]. Ann Anat, 2011, 193(2): 156-162. doi: 10.1016/j.aanat.2010.12.001 [11] 韩佳骆, 马学晓, 周传利, 等. 采用超声骨刀辅助椎板间入路脊柱内镜治疗重度钙化型腰椎间盘突出症的疗效观察[J]. 骨科临床与研究杂志, 2024, 9(1): 4-10.HAN J L, MA X X, ZHOU C L, et al. Observation on the curative effect of spinal endoscopy assisted by ultrasonic bone knife interlaminar approach in the treatment of severe calcified lumbar disc herniation[J]. Journal of Orthopaedic Clinical and Research, 2024, 9(1): 4-10. [12] YU L, WEN J K, WANG S, et al. Removal of calcified lumbar disc herniation with endoscopic-matched ultrasonic osteotome: our preliminary experience[J]. Br J Neurosurg, 2020, 34(1): 80-85. doi: 10.1080/02688697.2019.1687850 [13] 韩康, 谭树森, 张政, 等. 靶向破黄法在单侧双通道脊柱内镜技术治疗腰椎间盘突出症中的临床疗效[J]. 中华全科医学, 2023, 21(4): 560-564, 571.HAN K, TAN S S, ZHANG Z, et al. Clinical analysis of targeted broken ligamentum flavum method of unilateral biportal endoscopy in the treatment of lumbar spinal stenosis[J]. Chinese Journal of General Practice, 2023, 21(4): 560-564, 571. [14] 谭芳, 孙兆忠, 胡鹏, 等. 单通道与双通道内镜下侧隐窝减压术治疗腰椎侧隐窝狭窄症的近期疗效比较[J]. 实用临床医药杂志, 2022, 26(20): 5-9.TAN F, SUN Z Z, HU P, et al. Comparison of short-term efficacy of uni-channel and dual-channel endoscopic lateral recess decompression on short-term efficacy for lumbar lateral recess stenosis[J]. Journal of Clinical Medicine in Practice, 2022, 26(20): 5-9. [15] 芦怀旺, 田霖, 胡鹏, 等. 单侧双通道内镜治疗单责任节段腰椎管狭窄症的短期临床疗效分析[J]. 中华全科医学, 2023, 21(3): 413-416. doi: 10.16766/j.cnki.issn.1674-4152.002896LU H W, TIAN L, HU P, et al. Short-term clinical effect analysis of unilateral biportal endoscopic surgery for of single responsible segment lumbar spinal stenosis[J]. Chinese Journal of General Practice, 2023, 21(3): 413-416. doi: 10.16766/j.cnki.issn.1674-4152.002896 [16] 王宁, 贝朝涌, 万健, 等. 单侧双通道脊柱内镜技术行腰椎椎间融合术学习曲线研究[J]. 中国修复重建外科杂志, 2022, 36(10): 1229-1233.WANG N, BEI C Y, WAN J, et al. Learning curve analysis of unilateral biportal endoscopic lumbar interbody fusion[J]. Chinese Journal of Reparative and Reconstructive Surgery, 2022, 36(10): 1229-1233. [17] 郑超, 刘俊朋, 马炜, 等. 三角技术在脊柱单侧双通道内镜手术中的应用: 38例临床病例比较研究[J]. 空军医学杂志, 2021, 37(5): 413-417.ZHENG C, LIU J P, MA W, et al. Application of triangulation technique in unilateral double-channel endoscopic spinal surgery: a comparative study of 38 clinical cases[J]. Air Force Medical Journal, 2021, 37(5): 413-417. [18] 中华中医药学会脊柱微创专家委员会, 中国康复医学会骨伤康复专业委员会, 中国医师协会骨科医师定期考核专业委员会脊柱外科专家组, 等. 单孔分体内镜技术治疗腰椎管狭窄症专家共识[J]. 实用骨科杂志, 2024, 30(3): 193-198.Minimally Invasive Spine Expert Committee of the Chinese Association of Traditional Chinese Medicine, Orthopaedic Rehabilitation Committee of Chinese Association of Rehabilitation Medicine, Spine Surger. Expert Consensus on the Treatment of Lumbar Spinal Stenosis Using One-hole Split Endoscopy Technique[J]. Journal of Practical Orthopaedics, 2024, 30(3): 193-198. [19] 谭芳, 张锋, 韩帅, 等. 单孔分体内镜技术治疗腰椎管狭窄症的临床疗效分析[J]. 中国修复重建外科杂志, 2024, 38(3): 337-341.TAN F, ZHANG F, HAN S, et al. Analysis of effectiveness of one-hole split endoscopy technique in treatment of lumbar spinal stenosis[J]. Chinese Journal of Reparative and Reconstructive Surgery, 2024, 38(3): 337-341. [20] ZHANG Y H, FENG B, HU P, et al. One-hole split endoscopy technique versus unilateral biportal endoscopy technique for L5-S1 lumbar disk herniation: analysis of clinical and radiologic outcomes[J]. J Orthop Surg Res, 2023, 18(1): 668. DOI: 10.1186/s13018-023-04159-9.