多学科协作下生活方式管理模式在精神分裂症合并代谢综合征患者中的应用

姚国利; 陈琳霞; 马灵亚

doi:10.16766/j.cnki.issn.1674-4152.003885

多学科协作下生活方式管理模式在精神分裂症合并代谢综合征患者中的应用

doi: 10.16766/j.cnki.issn.1674-4152.003885

1.
绍兴市第七人民医院精神科，浙江绍兴 312000
2.
绍兴市第七人民医院质控科
3.
绍兴市第七人民医院公卫科

基金项目:

浙江省医药卫生科技计划项目 2022ZH062

详细信息

通讯作者:
姚国利，E-mail：cxdnzs888@163.com

中图分类号: R749.3
计量
- 文章访问数: 10
- HTML全文浏览量: 5
- PDF下载量: 3
- 被引次数: 0
出版历程
- 收稿日期: 2024-10-22
- 网络出版日期: 2025-03-27

Application of multidisciplinary collaboration lifestyle management model in schizophrenia patients with metabolic syndrome

1.
Department of Psychiatry, Shaoxing Seventh People ' s Hospital, Shaoxing, Zhejiang 312000, China

摘要

摘要: 目的采用多学科协作下生活方式管理模式对精神分裂症合并代谢综合征患者进行生活方式干预，观察其对患者精神症状、代谢指标及生活质量的影响，为精神分裂症合并代谢综合征患者制定生活方式管理方案提供理论依据。方法采用随机数字表法将2023年1月—2024年6月绍兴市第七人民医院收治的152例精神分裂症合并代谢综合征患者分为对照组(76例)和观察组(76例)。对照组应用常规生活方式干预方法，观察组采用多学科协作下生活方式管理模式。比较2组患者干预前后精神症状、代谢指标及生活质量情况。结果干预3个月后，观察组阳性和阴性症状量表(PANSS)总分为(37.96±4.27)分，低于对照组的(49.64±5.04)分，差异有统计学意义(P＜0.05)；观察组主要代谢指标[BMI、腰围、空腹血糖(FBG)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)]均优于对照组(P＜0.05)；观察组精神分裂症生活质量量表(SQLS)总分为(68.13±6.00)分，低于对照组的(85.15±8.27)分，差异有统计学意义(F=12.886, P＜0.001)。结论多学科协作下生活方式管理模式可促进精神分裂症合并代谢综合征患者病情恢复，改善代谢指标，提高患者生活质量。
- 精神分裂症 /
- 代谢综合征 /
- 多学科协作 /
- 生活方式管理 /
- 生活质量
Abstract: Objective To analyze the impact of a multidisciplinary lifestyle management model on the lifestyle intervention of patients diagnosed with both schizophrenia and metabolic syndrome. In addition, the study will observe its effects on patients ' mental symptoms, metabolic indicators and quality of life. And to provide a theoretical basis for lifestyle management plans for patients diagnosed with both schizophrenia and metabolic syndrome. Methods A total of 152 patients admitted to Shaoxing Seventh People ' s Hospital, from January 2023 to June 2024 were randomly divided into a control group and an observation group, with 76 patients in each group. The control group received routine lifestyle intervention methods, while the observation group adopted a multidisciplinary collaborative lifestyle management model. The study will compare the mental symptoms, metabolic indicators, and quality of life of the two groups of patients before and the after intervention. Results Following a period of three months, the total score of the positive and negative symptom scale (PANSS) in the observation group was found to be (37.96±4.27) points, which was lower than that of the control group [(49.64±5.04) points]. This difference was found to be statistically significant (P < 0.05); Furthermore, the main metabolic indicators of the observation group, including BMI, waist circumference, fasting blood glucose (FBG), triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C), were superior to those of the control group, and the differences were statistically significant (P < 0.05); The total score of the schizophrenia quality of life scale (SQLS) in the observation group was (68.13±6.00) points, which was lower than that in the control group [(85.15±8.27) points], and the difference was statistically significant (F=12.886, P < 0.001). Conclusion A multidisciplinary lifestyle management model has been shown to promote the recovery of patients diagnosed with both schizophrenia and metabolic syndrome. Furthermore, improvements in metabolic indicators and an enhancement in quality of life have been observed.
- Schizophrenia /
- Metabolic syndrome /
- Multidisciplinary collaboration /
- Lifestyle management /
- Quality of life

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表 1 2组精神分裂症合并代谢综合征患者一般情况比较

Table 1. Comparison of the general conditions of patients with schizophrenia combined with metabolic syndrome in 2 groups

组别	例数	性别(例)		年龄(x±s，岁)	文化程度(例)			婚姻状况(例)		病程(x±s，年)
组别	例数	男性	女性	年龄(x±s，岁)	初中及以下	中专及高中	大专及以上	未婚/离异	已婚	病程(x±s，年)
对照组	76	40	36	45.87±6.65	12	28	6	34	42	2.37±0.54
观察组	76	37	39	46.02±7.13	14	29	33	27	49	2.41±0.59
统计量		0.237^a		0.134^b	0.302^a			1.342^a		0.436^b
P值		0.626		0.893	0.860			0.247		0.663
注：^a为χ²值，^b为t值。

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表 2 2组精神分裂症合并代谢综合征患者精神症状比较(x±s，分)

Table 2. Comparison of mental symptoms in two groups of schizophrenic patients with metabolic syndrome(x±s, points)

组别	例数	阳性症状量表		阴性症状量表		一般精神病理症状量表		总分
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后
对照组	76	27.93±5.40	14.28±3.15^b	24.88±4.89	18.52±3.13^b	20.73±3.17	16.58±2.99^b	74.94±8.97	49.64±5.04^b
观察组	76	28.11±4.94	10.66±2.31^b	24.67±5.11	13.06±3.04^b	21.28±3.34	12.62±2.18^b	75.77±9.33	37.96±4.27^b
统计量		0.241^a	7.262^c	0.259^a	9.371^c	1.041^a	8.401^c	0.559^a	13.466^c
P值		0.831	＜0.001	0.796	＜0.001	0.299	＜0.001	0.577	＜0.001
注：^a为t值，^c为F值。与同组内干预前比较，^bP < 0.05。

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表 3 2组精神分裂症合并代谢综合征患者主要代谢指标(x±s)

Table 3. Main metabolic indexes of patients with schizophrenia combined with metabolic syndrome in 2 groups(x±s)

组别	例数	BMI		腰围(cm)		FBG(mmol/L)		TG(mmol/L)		HDL-C(mmol/L)
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后
对照组	76	27.10±3.04	26.51±3.29	94.24±10.13	90.17±8.29^b	5.94±0.90	5.51±1.24	2.94±0.93	2.87±0.86	0.97±0.41	1.14±0.32^b
观察组	76	26.87±2.99	24.73±2.28^b	93.81±10.25	85.06±6.33^b	5.96±1.02	4.81±0.83^b	3.02±1.00	2.08±0.75^b	1.04±0.56	1.58±0.39^b
统计量		0.470^a	3.406^c	0.260^a	6.311^c	0.128^a	3.971^c	0.511^a	5.733^c	0.879^a	6.892^c
P值		0.639	0.001	0.795	＜0.001	0.898	＜0.001	0.610	＜0.001	0.381	＜0.001
注：^a为t值，^c为F值。与同组内干预前比较，^bP < 0.05。

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表 4 2组精神分裂症合并代谢综合征患者生活质量比较(x±s，分)

Table 4. Comparison of quality of life in 2 groups of patients with schizophrenia combined with metabolic syndrome(x±s)

组别	例数	心理社会维度		动力和精力维度		症状及药物不良反应维度		总分
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后
对照组	76	44.29±8.97	38.74±6.42^b	20.86±4.36	20.11±4.14	28.62±5.77	26.72±4.36^b	94.50±10.33	85.15±8.27^b
观察组	76	44.51±8.16	30.18±5.82^b	21.20±4.17	15.22±3.74^b	28.02±5.41	21.17±3.85^b	95.13±9.98	68.13±6.00^b
统计量		0.158^a	8.012^c	0.791^a	6.937^c	0.661^a	4.392^c	0.382^a	12.886^c
P值		0.875	＜0.001	0.624	＜0.001	0.509	＜0.001	0.703	＜0.001
注：^a为t值，^c为F值。与同组内干预前比较，^bP < 0.05。

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