腕管综合征患者高频超声纹理特征及其诊断价值分析

邹庆国; 徐华军; 范慧慧; 金强; 季国飞

doi:10.16766/j.cnki.issn.1674-4152.003886

腕管综合征患者高频超声纹理特征及其诊断价值分析

doi: 10.16766/j.cnki.issn.1674-4152.003886

1.
湖州市中心医院超声科，浙江湖州313000
2.
上海瑞金医院超声科，上海 200025

基金项目:

浙江省医药卫生科技计划项目 2022RC263

详细信息

通讯作者:
邹庆国，E-mail：zqg0113@163.com

中图分类号: R445.1 R658.2
计量
- 文章访问数: 10
- HTML全文浏览量: 3
- PDF下载量: 1
- 被引次数: 0
出版历程
- 收稿日期: 2024-01-26
- 网络出版日期: 2025-03-27

Texture characteristics of high frequency ultrasound in patients with carpal tunnel syndrome and its diagnostic value

1.
Department of Ultrasound, Huzhou Central Hospital, Huzhou, Zhejiang 313000, China

摘要

摘要: 目的采用高频超声分析腕管综合征患者的纹理特征，并分析高频超声纹理特征对腕管综合征的诊断价值，以期为该病的诊断提供更好的方法。方法以2021年1月—2023年12月湖州市中心医院收治的148例腕管综合征患者为病例组，纳入同期因其他因素就诊的100例非腕管综合征患者为对照组。对比2组患者高频超声纹理特征，绘制ROC曲线分析高频超声纹理特征对腕管综合征的诊断价值。结果病例组均值、标准差、变异系数以及直方图熵均低于对照组，偏度、峰值、亮度熵以及中值均高于对照组(P < 0.05)；病例组像素均值比、同深度均值比、中值比、同深度中值比、Q0.5、Q0.6、Q0.7、Q0.8、Q0.9、Q1均低于对照组，Q0、Q0.05、Q0.1以及Q0.15均高于对照组(P < 0.05)；病例组厚度最大值、厚度中值、厚度均值、长度最大值、长度中值、长度均值、病灶面积、长轴、短轴、离心率以及病灶周长均小于对照组(P < 0.05)；灰阶共生矩阵、形态学特征以及一阶统计量联合诊断腕管综合征患者的AUC(0.934)显著高于单一灰阶共生矩阵AUC(0.762)、形态学特征AUC(0.884)以及一阶统计量AUC(0.753)。结论高频超声纹理特征分析中灰阶共生矩阵、形态学特征以及一阶统计量对腕管综合征患者具有较高的诊断价值，且3种联合的诊断价值更高。
- 腕管综合征 /
- 高频超声 /
- 纹理特征 /
- 诊断价值
Abstract: Objective To analyze the texture features of patients with carpal tunnel syndrome by high-frequency ultrasound, and to analyze the diagnostic value of high-frequency ultrasound texture features for carpal tunnel syndrome, so as to provide a better method for the diagnosis of this disease. Methods From January 2021 to December 2023, 148 patients with carpal tunnel syndrome in Huzhou Central Hospital were taken as the case group, and 100 patients with non-carpal tunnel syndrome who were treated for other factors during the same period were included as control group. Compare the texture features of high-frequency ultrasound between the two groups, draw the ROC curve, and analyze the diagnostic value of high-frequency ultrasound texture features in carpal tunnel syndrome. Results The mean value, standard deviation, coefficient of variation, and histogram entropy of the case group were lower than those of the control group, while the skewness, peak value, brightness entropy, and median value were higher than those of the control group (P < 0.05). The average ratio of pixels, average ratio of the same depth, median ratio, median ratio of the same depth, Q0.5, Q0.6, Q0.7, Q0.8, Q0.9, and Q1 in the case group were lower than those in the control group, while Q0, Q0.05, Q0.1 and Q0.15 were higher than those in the control group (P < 0.05). The maximum thickness, median thickness, average thickness, maximum length, median length, average length, lesion area, major axis, minor axis, eccentricity, and lesion circumference in the case group were all lower than those in the control group (P < 0.05). The AUC (0.934) of gray level co-occurrence matrix, morphological features, and first-order statistics in the diagnosis of elbow syndrome was significantly higher than that of single and gray level co-occurrence matrix AUC (0.762), morphological features AUC (0.884) and first-order statistics AUC (0.753). Conclusion Gray-level co-occurrence matrix, morphological features, and first-order statistics in texture feature analysis of high-frequency ultrasound have high diagnostic value for patients with carpal tunnel syndrome, and the combination of the three is more valuable.
- Carpal tunnel syndrome /
- High frequency ultrasound /
- Texture features /
- Diagnostic value

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图 1 超声纹理特征诊断腕管综合征的ROC曲线

Figure 1. ROC curve for the diagnosis of carpal tunnel syndrome using ultrasonic texture characteristics

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表 1 2组患者一阶统计量比较(x±s)

Table 1. Comparison of first-order statistics between two groups of patients

组别	例数	均值	标准差	变异系数	偏度	峰值	直方图熵	亮度熵	中值
病例组	148	0.25±0.06	0.08±0.02	0.34±0.08	0.79±0.25	4.31±1.25	6.23±0.29	0.99±0.01	0.17±0.05
对照组	100	0.27±0.05	0.10±0.01	0.40±0.07	0.42±0.21	3.28±0.97	6.64±0.22	0.97±0.01	0.12±0.06
t值		2.848	10.394	6.247	12.593	7.289	12.639	15.450	6.875
P值		0.005	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001

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表 2 2组患者灰阶共生矩阵纹理特征比较(x±s)

Table 2. Comparison of gray-level co-occurrence matrix texture features between two groups of patients(x±s)

组别	例数	像素均值比	同深度均值比	中值比	同深度中值比	Q0	Q0.05	Q0.1
病例组	148	1.29±0.41	3.15±1.05	0.79±0.18	0.73±0.17	0.06±0.03	0.13±0.04	0.15±0.06
对照组	100	1.43±0.51	9.64±3.27	0.86±0.22	0.83±0.27	0.02±0.01	0.11±0.03	0.13±0.03
t值		2.290	19.190	2.640	3.289	15.032	4.493	3.465
P值		0.023	< 0.001	0.009	0.001	< 0.001	< 0.001	0.001

组别	例数	Q0.15	Q0.5	Q0.6	Q0.7	Q0.8	Q0.9	Q1
病例组	148	0.17±0.05	0.24±0.06	0.26±0.06	0.28±0.05	0.31±0.07	0.36±0.07	0.59±0.12
对照组	100	0.15±0.04	0.26±0.05	0.28±0.07	0.31±0.06	0.35±0.07	0.39±0.09	0.64±0.09
t值		3.487	2.848	2.336	4.125	4.414	2.808	3.745
P值		0.001	0.005	0.021	< 0.001	< 0.001	0.006	< 0.001

下载: 导出CSV

表 3 2组患者形态学特征比较(x±s)

Table 3. Comparison of morphological characteristics between two groups of patients(x±s)

组别	例数	厚度最大值(cm)	厚度中值(cm)	厚度均值(cm)	长度最大值(cm)	长度中值(cm)	长度均值(cm)	病灶面积(cm²)	长轴(cm)	短轴(cm)	离心率(cm)	病灶周长(cm)
病例组	148	0.17±0.02	0.14±0.02	0.13±0.01	0.47±0.15	0.38±0.12	0.34±0.10	0.07±0.03	0.55±0.21	0.17±0.02	0.92±0.07	1.24±0.44
对照组	100	0.24±0.05	0.19±0.04	0.19±0.04	1.03±0.41	0.72±0.31	0.67±0.31	0.34±0.19	1.31±0.34	0.25±0.05	0.96±0.03	2.62±0.87
t值		13.300	11.562	14.693	13.080	10.451	10.290	14.092	19.931	15.199	6.164	14.647
P值		< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001

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表 4 超声纹理特征对腕管综合征患者的诊断价值

Table 4. Diagnostic value of ultrasonic texture features in patients with carpal tunnel syndrome

纹理特征	AUC	95% CI	灵敏度	特异度	约登指数	Cut-off值	P值	SE
灰阶共生矩阵	0.762	0.704~0.813	98.60	68.00	0.67	5.54	＜0.01	0.040
形态学特征	0.884	0.837~0.921	95.30	71.00	0.66	2.01	＜0.01	0.024
一阶统计量	0.753	0.694~0.805	60.10	85.00	0.45	4.15	＜0.01	0.031
联合	0.934	0.896~0.962	94.60	83.00	0.78		＜0.01	0.017

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