中医序贯式运动方案在双相情感障碍抑郁期患者中的应用效果

李萍; 冯虹; 张惠玲; 杨晓妍; 何月敏

doi:10.16766/j.cnki.issn.1674-4152.003968

中医序贯式运动方案在双相情感障碍抑郁期患者中的应用效果

doi: 10.16766/j.cnki.issn.1674-4152.003968

1.
绍兴市第七人民医院焦虑障碍科，浙江绍兴 312000
2.
绍兴市第七人民医院心身障碍科一病区(睡眠病区)
3.
绍兴市第七人民医院门诊部

基金项目:

浙江省医药卫生科技计划项目 2022RC279

详细信息

通讯作者:
李萍，E-mail：yuhewanshiwojia163@163.com

中图分类号: R749.05
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- 文章访问数: 2
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出版历程
- 收稿日期: 2025-01-14
- 网络出版日期: 2025-06-30

Application effect of traditional Chinese medicine sequential exercise program in patients with bipolar disorder in depression

1.
Department of Anxiety Disorders, Shaoxing Seventh People' s Hospital, Shaoxing, Zhejiang 312000, China

摘要

摘要: 目的分析中医序贯式运动方案在双相情感障碍(BD)抑郁期患者中的应用效果，及其对患者抑郁症状、正性情绪体验及睡眠质量的影响，为BD抑郁期患者运动干预提供新的参考依据。方法选取2023年1月—2024年10月绍兴市第七人民医院收治的136例双相情感障碍抑郁期患者作为研究对象，采用随机数字表法分为对照组(68例)和观察组(68例)。对照组应用常规护理干预，观察组在对照组基础上应用中医序贯式运动方案。比较2组患者干预前后抑郁症状、情绪状况及睡眠质量。结果干预后，观察组患者汉密尔顿抑郁量表-24项(HAMD-24)评分为(7.50±2.28)分，低于对照组[(11.23±3.49)分，P＜0.05]；观察组患者正性和负性情绪自评量表(PANAS)中正性情绪评分为(34.66±3.25)分，高于对照组的(30.29±4.10)分，负性情绪评分为(17.12±2.55)分，低于对照组的(19.03±3.14)分，差异均有统计学意义(P＜0.05)；观察组患者匹兹堡睡眠质量指数(PSQI)总分及7个维度得分均低于对照组(P＜0.05)。结论中医序贯式运动方案应用于BD抑郁期患者中，可有效缓解患者抑郁症状，提高正性情绪体验，改善患者睡眠质量。
- 双相情感障碍抑郁期 /
- 中医序贯式运动方案 /
- 抑郁症状 /
- 正负性情绪 /
- 睡眠质量
Abstract: Objective To analyze the effect of traditional Chinese medicine sequential exercise program in patients with bipolar disorder (BD) in depression, and to provide a new reference for exercise intervention in patients with BD depression. Methods A total of 136 patients with bipolar disorder and depression admitted to Shaoxing Seventh People' s Hospital from January 2023 to October 2024 were selected as the research subjects and randomly divided into a control group and an observation group, with 68 patients in each group. The control group received routine nursing care, while the observation group received a sequential exercise regimen based on traditional Chinese medicine on the basis of the control group. The depressive symptoms, emotional status, and sleep quality of two groups of patients before and after intervention were compared. Results After intervention, the Hamilton depression scale-24 (HAMD-24) score for the observation group was (7.50±2.28) points, which was lower than that in the control group [(11.23±3.49) points, P < 0.05]. The positive emotion score in the observation group' s positive and negative affect scale (PANAS) was (34.66±3.25) points, which was higher than that in the control group [(30.29±4.10) points], the negative emotion score was (17.12±2.55) points, which was lower than that in the control group [(19.03±3.14) points, P < 0.05]. The total score and seven factor scores of Pittsburgh sleep quality indes (PSQI) in the observation group were lower than those in the control group (P < 0.05). Conclusion The application of traditional Chinese medicine sequential exercise program in patients with bipolar disorder depression can effectively alleviate depressive symptoms, improve positive emotional experiences, and enhance sleep quality.
- Bipolar disorder in depression /
- Traditional Chinese medicine sequential exercise program /
- Depressive symptoms /
- Positive and negative emotions /
- Sleep quality

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表 1 2组双相情感障碍抑郁期患者一般资料比较

Table 1. Comparison of general information between two groups of bipolar depression patients

组别	例数	性别(例)		年龄(x±s，岁)	婚姻状况(例)			病程时间(x±s，月)	受教育年限(x±s，年)
组别	例数	男性	女性	年龄(x±s，岁)	已婚	未婚	离异	病程时间(x±s，月)	受教育年限(x±s，年)
对照组	68	40	28	33.86±4.02	30	34	4	8.53±2.16	15.46±3.77
观察组	68	37	31	34.01±3.73	33	28	7	8.41±2.34	15.53±3.64
统计量		0.269^a		0.226^b	1.542^a			0.311^b	0.110^b
P值		0.604		0.822	0.463			0.756	0.912
注：^a为χ²值，^b为t值。

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表 2 2组双相情感障碍抑郁期患者抑郁症状比较(x±s，分)

Table 2. Comparison of depressive symptoms between two groups of bipolar depression patients (x±s, points)

组别	例数	HAMD-24
组别	例数	干预前	干预后
对照组	68	31.55±3.71	11.23±3.49^b
观察组	68	31.42±3.46	7.50±2.28^b
统计量		0.211^a	6.659^c
P值		0.833	＜0.001
注：^a为t值，^c为F值；与同组干预前比较，^bP＜0.05。

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表 3 2组双相情感障碍抑郁期患者情绪状况比较(x±s，分)

Table 3. Comparison of emotional status between two groups of bipolar depression patients (x±s, points)

组别	例数	正性情绪		负性情绪
组别	例数	干预前	干预后	干预前	干预后
对照组	68	25.72±4.82	30.29±4.10^b	24.62±4.15	19.03±3.14^b
观察组	68	26.30±5.31	34.66±3.25^b	25.11±3.92	17.12±2.55^b
统计量		0.667^a	6.033^c	0.708^a	3.346^c
P值		0.506	＜0.001	0.480	0.001
注：^a为t值，^c为F值；与同组干预前比较，^bP＜0.05。

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表 4 2组双相情感障碍抑郁期患者睡眠质量比较(x±s，分)

Table 4. Comparison of sleep quality between two groups of bipolar depression patients (x±s, points)

组别	例数	睡眠质量		入睡时间		睡眠时间		睡眠效率
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后
对照组		2.06±0.44	1.67±0.49^b	1.83±0.37	1.46±0.61^b	1.59±0.48	1.45±0.56	1.68±0.56	1.43±0.41^b
观察组		2.10±0.31	0.93±0.22^b	1.85±0.40	1.02±0.29^b	1.62±0.63	1.11±0.27^b	1.62±0.59	0.99±0.20^b
统计量		0.613^a	9.592^c	0.303^a	6.233^c	0.312^a	3.421^c	0.304^a	10.218^c
P值		0.541	＜0.001	0.763	＜0.001	0.755	＜0.001	0.762	＜0.001

组别	例数	睡眠障碍		催眠药物使用		日间功能		总分
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后
对照组		2.01±0.30	1.58±0.67^b	1.59±0.50	1.47±0.67	2.13±0.27	1.50±0.41^b	16.73±3.78	12.18±2.36^b
观察组		1.94±0.41	0.90±0.25^b	1.62±0.66	1.13±0.43^b	2.09±0.31	1.03±0.34^b	16.49±3.54	8.12±1.40^b
统计量		1.136^a	9.833^c	0.222^a	3.285^c	0.802^a	4.273^c	0.382^a	11.859^c
P值		0.258	＜0.001	0.825	＜0.001	0.424	＜0.001	0.703	＜0.001
注：^a为t值，^c为F值；与同组干预前比较，^bP＜0.05。

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