Application of perinatal nutrition-metabolism combined evidence-based nursing model in patients with gestational diabetes mellitus
-
摘要:
目的 妊娠期糖尿病可导致母婴不良结局,单一护理模式对妊娠结局的改善效果有限。本研究旨在构建并验证基于循证护理的营养-代谢护理模式在围产期糖尿病患者中的应用效果。 方法 选取2024年2月—2025年1月舟山市妇女儿童医院收治的妊娠28~35周孕妇,诊断为妊娠期糖尿病的围产期患者100例为研究对象。使用随机数表法将患者分为对照组(50例)和研究组(50例),对照组接受常规护理,研究组在对照组的基础上实施围产期营养-代谢联合循证护理模式。比较2组患者的血脂水平、血糖水平,孕期体重增长情况、自然分娩率、住院时间、产后72 h纯母乳喂养率,妊娠期及产后合并症、并发症发生率,新生儿不良结局发生率。 结果 干预后,研究组患者的HDL、LDL、TG、TC水平均显著低于对照组(P<0.05),且数值在正常范围内;研究组患者的FBG和2hPG均显著低于对照组(P<0.05);研究组患者的体重增长低于对照组(P<0.05)。研究组患者的自然分娩率和产后72 h纯母乳喂养率分别为76.0%(38/50)和92.0%(46/50),均优于对照组[58.0%(29/50)和76.0%(38/50),P<0.05]。研究组患者住院时间短于对照组[(6.22±1.68)d vs. (7.02±2.17)d,P<0.05)];研究组患者的不良妊娠结局发生率和新生儿不良结局发生率均低于对照组(P<0.05)。 结论 围产期营养-代谢联合循证护理模式能够改善围产期糖尿病患者的血脂和血糖水平,控制体重增长,降低不良妊娠结局发生率。 Abstract:Objective Gestational diabetes mellitus (GDM) has been associated with adverse maternal and infant outcomes, and the single nursing model has been demonstrated to have a limited effect on improving pregnancy outcomes. The objective of this study is to develop and validate the application of the nutrition and metabolism nursing model, grounded in evidence-based nursing principles, for patients diagnosed with perinatal diabetes mellitus. Methods A total of 100 perinatal patients diagnosed with gestational diabetes mellitus at 28-35 weeks of gestation and admitted to Zhoushan Women and Children's Hospital from February 2024 to January 2025 were selected as the research subjects. The patients were divided into control group (n=50) and study group (n=50) by random number table method. The control group received routine nursing care, while the study group received perinatal nutrition-metabolism combined evidence-based nursing care, based on the findings of the control group. The investigation focused on a comprehensive set of health metrics, including blood lipid levels, blood glucose levels, weight gain during pregnancy, natural delivery rate, length of hospital stay and exclusive breastfeeding rate within 72 hours after delivery. A comparative analysis was conducted between the two groups, with the objective of identifying potential disparities in health outcomes. The present study will examine the incidence of complications during pregnancy and postpartum, as well as the incidence of adverse neonatal outcomes. Results Subsequent to the intervention, the levels of HDL, LDL, TG and TC in the study group were found to be significantly lower than those in the control group (P < 0.05), and the values were within the normal range. The FBG and 2hPG of levels of the study group were found to be significantly lower than those of the control group (P < 0.05). The weight gain of the study group was lower than that of the control group (P < 0.05). The natural delivery rate and exclusive breastfeeding rate within 72 hours postpartum in the study group were 76.0% (38/50) and 92.0% (46/50), respectively, which were superior to those in the control group [58.0% (29/50) and 76.0% (38/50), P < 0.05]. The length of hospital stay in the study group was found to be shorter than that in the control group [(6.22±1.68) d vs. (7.02±2.17) d, P < 0.05]. The incidence of adverse pregnancy outcomes and adverse neonatal outcomes in the study group was lower than that in the control group (P < 0.05). Conclusion The perinatal nutrition-metabolism combined evidence-based nursing model has been demonstrated to improve the blood lipid and blood glucose levels in patients with perinatal diabetes mellitus, control the weight gain, and reduce the incidence of adverse pregnancy outcomes. -
表 1 2组妊娠期糖尿病患者血脂指标水平比较(x±s, mmol/L)
Table 1. Comparison of lipid profile levels between the two groups of patients with gestational diabetes mellitus (x±s, mmol/L)
组别 例数 HDL LDL TG TC 对照组 50 2.01±0.31 3.89±0.63 3.61±1.55 7.15±1.10 研究组 50 1.85±0.35 3.42±0.77 3.02±1.17 6.14±1.31 t值 2.419 3.341 2.148 4.175 P值 0.017 0.001 0.034 <0.001 表 2 2组妊娠期糖尿病患者糖代谢水平比较(x±s, mmol/L)
Table 2. Comparison of glycemic control between the two groups of patients with gestational diabetes mellitus (x±s, mmol/L)
组别 例数 FBG 2hPG 干预前 干预后 干预前 干预后 对照组 50 5.68±0.59 5.36±0.78 8.62±1.36 6.05±1.13 研究组 50 5.62±0.67 4.41±0.42 8.44±1.23 5.59±1.14 统计量 0.538a 8.231b 0.699a 8.542b P值 0.629 0.021 0.612 0.016 注:a为t值,b为F值。 表 3 2组妊娠期糖尿病患者恢复情况比较
Table 3. Comparison of glycemic control status between the two groups of patients with gestational diabetes mellitus
组别 例数 孕期体重增长情况(x±s,kg) 自然分娩[例(%)] 住院时间(x±s,d) 产后72 h纯母乳喂养[例(%)] 对照组 50 10.65±3.69 29(58.0) 7.02±2.17 38(76.0) 研究组 50 9.26±3.08 38(76.0) 6.22±1.68 46(92.0) 统计量 2.045a 7.636b 2.061a 4.714b P值 0.043 0.005 0.042 0.030 注:a为t值,b为χ2值。 -
[1] 骆丽娅, 翁孝刚. 妊娠期糖尿病患者血脂水平与血糖控制的关系研究[J]. 黑龙江医药, 2025, 38(1): 202-204.LUO L Y, WENG X G. Study on the Relationship between Blood Lipid Levels and Blood Glucose Control in Patients with Gestational Diabetes Mellitus[J]. Heilongjiang Medicine, 2025, 38(1): 202-204. [2] EWERS B, BLOND M B, KELSTRUP L, et al. Effect of intensive nutrition training, education and support versus standard therapy in reducing the need for insulin therapy in gestational diabetes (INTENSE-GDM): a protocol for a randomised controlled single-centre trial in Denmark[J]. BMJ Open, 2025, 15(2): e089231. DOI: 10.1136/bmjopen-2024-089231. [3] MADIWALE S, JOSHI N, RANDHIR K, et al. Longitudinal assessment of maternal micronutrients (folate and vitamin B12) and homocysteine levels in women who develop gestational diabetes mellitus[J]. Eur J Clin Nutr, 2025, 79(6): 520-528. doi: 10.1038/s41430-025-01581-6 [4] 黄小艳, 饶靖红, 刘江英. 远程管理联合跨文化理论在妊娠期糖尿病产前管理中的应用[J]. 福建医药杂志, 2025, 47(1): 113-115.HUANG X Y, RAO J H, LIU J Y. The Application of Remote Management Combined with Cross-cultural Theory in Prenatal Management of Gestational Diabetes Mellitus[J]. Fujian Journal of Medicine, 2025, 47(1): 113-115. [5] 常颖, 章露文, 丁雪雪. 个体化全程营养干预模式对妊娠期糖尿病孕妇的影响研究[J]. 现代医药卫生, 2022, 38(9): 1446-1450, 1454.CHANG Y, ZHANG L W, DING X X. Research on the Impact of Individualized whole-course Nutrition Intervention Model on Pregnant Women with Gestational Diabetes Mellitus[J]. Journal Modern Medicine Health, 2022, 38(9): 1446-1450, 1454. [6] ENACHE R M, ROŞU O A, PROFIR M, et al. Correlations between gut microbiota composition, medical nutrition therapy, and insulin resistance in pregnancy: a narrative review[J]. Int J Mol Sci, 2025, 26(3): 1372. DOI: 10.3390/ijms26031372. [7] 李英, 郭玲利, 王燕梅. 营养干预联合规范化治疗在妊娠期糖尿病孕妇中的应用[J]. 中国医学创新, 2025, 22(2): 130-134.LI Y, GUO L L, WANG Y M. The application of nutritional intervention combined with standardized treatment in pregnant women with gestational diabetes mellitus[J]. Chinese Medical Innovation, 2025, 22(2): 130-134. [8] 贾梦兰, 郭慧兰, 司安伟, 等. 个性化营养指导联合健康教育在妊娠期糖尿病患者围产期保健中的应用[J]. 海南医学, 2025, 36(1): 134-138.JIA M L, GUO H L, SI A W, et al. The Application of Personalized Nutrition Guidance Combined with Health Education in Perinatal Health Care for Patients with Gestational Diabetes Mellitus[J]. Hainan Medical Journal, 2025, 36(1): 134-138. [9] BUKARI M, ABUBAKARI A, MALECHI H, et al. Resource constraints, patient emotions, and therapy: experiences of healthcare providers in the screening and management of gestational diabetes mellitus in northern Ghana[J]. BMC Health Serv Res, 2025, 25(1): 209. DOI: 10.1186/s12913-025-12262-2. [10] 蔡素霞, 付泽霞, 宁飞燕. 妊娠期糖尿病患者产后高血糖转归的影响因素及风险预测模型构建[J]. 医药论坛杂志, 2025, 46(4): 365-371.CAI S X, FU Z X, NING F Y. Influencing Factors and Risk Prediction Model Construction of Postpartum Hyperglycemia Prognosis in Patients with Gestational Diabetes mellitus[J]. Journal of Medical Forum, 2025, 46(4): 365-371. [11] SMITH R, BORG R, WONG V, et al. Associations between carbohydrate intake behaviours and glycaemia in gestational diabetes: a prospective observational study[J]. Nutrients, 2025, 17(3): 400. DOI: 10.3390/nu17030400. [12] 吴碧云. 个性化护理策略的早期营养干预对妊娠期糖尿病孕产妇母婴结局及免疫功能的影响[J]. 黑龙江中医药, 2023, 52(1): 67-69.WU B Y. The influence of early nutritional intervention of personalized nursing strategies on maternal and infant outcomes and immune function of pregnant and postpartum women with gestational diabetes mellitus[J]. Heilongjiang Journal of Traditional Chinese Medicine, 2023, 52(1): 67-69. [13] 萨那斯日古楞, 王丹. 妊娠期糖尿病对孕妇围产期认知功能的影响[J]. 哈尔滨医科大学学报, 2022, 56(5): 516-519.SANAS Z G, WANG D. The influence of gestational diabetes mellitus on perinatal cognitive function of pregnant women[J]. Journal of Harbin Medical University, 2022, 56(5): 516-519. [14] 袁玲. 围产期优质整体护理在GDM患者中的应用[J]. 中外医学研究, 2025, 23(1): 79-82.YUAN L. The application of high-quality holistic Perinatal care in patients with Gestational Diabetes Mellitus (GDM)[J]. Chinese and Foreign Medical Research, 2025, 23(1): 79-82. [15] 崔斐. 首诊-复诊-住院-产后管理的模块化护理干预在妊娠期糖尿病患者围产期中的应用[J]. 广州医药, 2022, 53(4): 56-59.CUI F. The application of modular nursing intervention of first visit - Follow-up visit - hospitalization - postpartum management in the perinatal period of patients with gestational diabetes mellitus[J]. Guangzhou Pharmaceutical, 2022, 53(4): 56-59. [16] 吴珊. 动态血糖监测系统指导的个体化营养及运动治疗在妊娠糖尿病治疗中的应用[J]. 江西医药, 2022, 57(7): 711-713.WU S. The application of individualized Nutrition and Exercise Therapy guided by continuous glucose Monitoring System in the Treatment of Gestational Diabetes mellitus[J]. Jiangxi Medicine, 2022, 57(7): 711-713. [17] 史慧芳. 个体化营养干预对妊娠糖尿病患者血糖及炎症反应控制效果的影响[J]. 中国医药导报, 2021, 18(34): 180-184.SHI H F. The influence of individualized nutritional intervention on the control effect of blood glucose and inflammatory response in patients with gestational diabetes mellitus[J]. Chin Med Herald, 2021, 18(34): 180-184. [18] 孙东华, 罗翠娟. 营养干预妊娠期糖尿病对血糖及妊娠结局的影响[J]. 河北医药, 2021, 43(15): 2362-2364.SUN D H, LUO C J. The influence of nutritional intervention on blood glucose and pregnancy outcome of gestational diabetes mellitus[J]. Hebei Med J, 2021, 43(15): 2362-2364. [19] 高宏, 刘丽萍. 孕期规范化管理方案在改善糖尿病产妇妊娠结局中的应用分析[J]. 宁夏医学杂志, 2021, 43(6): 560-562.GAO H, LIU L P. Application Analysis of Standardized Management Program during Pregnancy in Improving Pregnancy Outcomes of Diabetic Parturients[J]. Ningxia Medical Journal, 2021, 43(6): 560-562. [20] 武晓华. 个体化医学营养治疗对妊娠期糖尿病患者糖脂代谢及妊娠结局的影响[J]. 临床医学研究与实践, 2021, 6(16): 107-109.WU X H. The influence of individualized medical nutrition therapy on glycolipid metabolism and pregnancy outcomes in patients with gestational diabetes mellitus[J]. Clinical Medical Research and Practice, 2021, 6(16): 107-109. [21] 刘铭忆, 马秀华. 妊娠期糖尿病妇女产后转归及随访的研究进展[J]. 中华全科医学, 2022, 20(1): 109-112, 116. doi: 10.16766/j.cnki.issn.1674-4152.002289LIU M Y, MA X H. - Research progress on Postpartum prognosis and Follow-up of Women with gestational diabetes mellitus[J]. Chinese Journal of General Practice, 2022, 20(1): 109-112, 116. doi: 10.16766/j.cnki.issn.1674-4152.002289 [22] 李阳. 在围产期对孕产妇开展营养健康教育对减少妊娠期合并症的意义[J]. 中国社区医师, 2021, 37(14): 170-171.LI Y. The significance of conducting nutrition and health education for pregnant and postpartum women during the perinatal period in reducing pregnancy-related complications[J]. Chinese Community Doctors, 2021, 37(14): 170-171. -
点击查看大图
计量
- 文章访问数: 2
- HTML全文浏览量: 2
- PDF下载量: 0
- 被引次数: 0
下载: