Abstract: Objective To adopt the clinical typical case analysis of medical disputes combined PBL in orthopedic clinical teaching,and investigate the feasibility and practical effect of this teaching method,and the influences on the learning strategies,motivation,academic record of student. Methods Total 84 clinical medicine undergraduate students practiced in our department from 2012 to 2013 were assigned into study group and control group.The study group received PBL combined with clinical typical case analysis of medical disputes,while the control group received conventional teaching methods.After the clinical practice teaching,the test scores were used to evaluate teaching achievements.The questionnaires were employed to assess the learning attitude and acceptance. Results The score in the study group was significantly higher than that in the control group.PBL model combined with medical dispute case analysis stimulated the interest of students in learning and their desire for knowledge,and improved the ability of students to analyze and solve clinical problems and skills of doctor-patient communication,train their of awareness of prevention of medical disputes and creative thinking. Conclusion Hot spots of college teaching reform is the reform of teaching methods,the purpose of reformation is to improve the students’ ability in clinical practice,comprehensive knowledge and self-learning.PBL combined with clinical typical case analysis of medical disputes is based on case teaching principles,emphasize on the learning in a meaningful context,which meet the laws of learning,help students develop the ability in clinical practice,also promote the growth of knowledge to improve student discipline and self-learning ability.This method has achieved good clinical teaching effectiveness,and is well received by students.The penetration of medical disputes prevention education for students in clinical practice together with the professional knowledge education will help the students to decrease the medical disputes in their works.It is worth application and promotion in the surgical teaching and clinical teaching.