Abstract: Objective To investigate the effect of traditional Chinese medicine injection combined with acupoint massage and early nursing intervention on the swelling of Pilon fracture,to provide reference for clinical nursing. Methods Eightycases of Pilon from January 2013 to January 2015 in our hospital were fracture patients as the research object.According to the random number table method,the patients were divided into the treatment group and the control group (40 cases),control group were given routine nursing,patients in the treatment group were treated with traditional Chinese medicine hot and cold spray combined with acupoint massage nursing intervention on the basis of routine nursing,nursing 5 days compared two groups of patients with clinical curative effect,the swelling time and nursing after 1,3 days after the changes of pain situation. Results Nursing care in the treatment group,the total efficiency was 97.50% (39/40) and in the control group,the total efficiency is 82.50% (33/40),in the treatment group,the total efficiency was significantly higher than that in the control group,the difference was statistically significant (P<0.05).The treatment group 1 and 3 days after the VAS scores were lower than the control group,the difference was statistically significant (P<0.05);treatment group,swelling time (5.01±0.49)d,which was significantly lower than that of the control group (P<0.05);treatment group,the total satisfaction rate was 100.00% (40/40) and in the control group,the total satisfaction rate was 82.50% (33/40),in the treatment group,the total satisfaction rate was significantly higher than that of the control group,the difference had statistical significance (P<0.05). Conclusion Hot and cold spray of traditional Chinese medicine combined with acupoint massage nursing intervention reduce the Pilon fracture patients with early swelling and the degree of pain,improve patient satisfaction,operation is convenient and has no serious adverse reactions,it is worth clinical attention.