Type analysis and related factors of 85 cases of rheumatoid arthritis patients with anemia
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摘要: 目的 探讨类风湿关节炎(rheumatoid arthritis,RA)患者合并贫血的类型及其相关因素。 方法 选取衢州市人民医院2012年1月—2014年12月3年间确诊的RA患者,在清晨空腹状态下,抽取静脉血送实验室进行相关指标检查。将得到的资料进行统计分析。 结果 合并慢性病性贫血(chronic disease anemia,ADC)27例,占总贫血的47.37%(27/57),缺铁性贫血(iron deficiency anemia,IDA)20例,占总贫血的35.09%(20/57),巨幼细胞性贫血(MA)10例,占总贫血的17.54%(10/57)。女性贫血发生率显著高于男性(P<0.05)。ADC患者与无贫血患者比较,强的松的用量显著增加(P<0.05),MA患者年龄显著高于无贫血患者(P<0.05);ADC患者与无贫血患者比较,病情活动度、血沉、C反应蛋白均显著增高(P均<0.05)。 结论 RA患者合并贫血的类型主要是慢性病性贫血和缺铁性贫血,与长期口服药物、病情活动度、血沉、C反应蛋白可能有关,RA患者并发贫血还需警惕和预防恶病质的出现,通过饮食增加营养摄入,补充蛋白质、维生素和矿物质,这对预防和避免贫血能起到重要作用。Abstract: Objective To investigate the type of anemia in patients with rheumatoid arthritis and related factors. Methods From December,2014 to January,2012,3 years,has a clear diagnosis and in the treatment of rheumatoid arthritis patients,in the early morning fasting state,the extraction of a certain amount of upper arm blood,laboratory test for related indicators.Statistical analysis of the obtained data. Results Twenty-seven cases of chronic disease anemia(ADC) accounted for 47.37%(27/57),20 cases of iron deficiency anemia(IDA),35.09%(20/57),10 cases(MA),17.54%(10/57).There were significant differences in gender distribution(P<0.05),and the incidence of anemia in women was higher than that in male.Patients with anemia of chronic disease compared with patients without anemia group,prednisone dosage increased significantly(P<0.01),the other two groups had no significant difference.Other factors,megaloblastic anemia patients and patients without anemia group,age was significantly increased(P<0.05);group of patients with anemia of chronic disease compared with patients without anemia group,disease activity,ESR,C reactive protein were significantly increased(P<0.05). Conclusion The type of rheumatoid arthritis patients with anemia of inflammation is the main chronic diseases anemia and iron deficiency anemia,and long-term oral drugs, rheumatoid arthritis disease activity,ESR,C reactive protein,rheumatoid joint inflammation in patients with anemia also need vigilance and prevention of cachexia,increase nutrition through diet intake of protein,vitamins and minerals,to prevent and avoid anemia can play an important role.
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Key words:
- Rheumatoid arthritis /
- Anemia /
- Related factors
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