Abstract: Objective To investigate the present situation level and influence factors of sleep disorders among the families of ICU patients,and provided a reference basis for clinical nurses to take targeted intervention to reduce the sleep disorders in families of ICU patients. Methods A total of 183 families of ICU patients were recruited from three first-class hospitals in Hangzhou by convenience sampling method.They were investigated with a self-designed information questionnaire,pittsburgh sleep quality index,mishel uncertainty in illness scale-family and beck anxiety inventory of ICU families.Mean,standard deviation and percentage were used for statistical description in general data of ICU families.The influence factors of sleep disorders among the relatives of ICU patients were analyzed using multiple stepwise regression analysis. Results The total score of pittsburgh sleep quality index among the families of ICU patients was 12.56±5.52,the total score of mishel uncertainty in illness scale-family among the families of ICU patients was 85.29±13.80,the total score of beck anxiety inventory among the families of ICU patients was 50.39±8.48.Pearson correlation analysis showed that pittsburgh sleep quality index among the families of ICU patients has a positive correlate between mishel uncertainty in illness scale-family and beck anxiety inventory,the correlation coefficient between pittsburgh sleep quality index and mishel uncertainty in illness range from 0.112 to 0.328,the correlation coefficient between pittsburgh sleep quality index and beck anxiety inventory range from 0.115 to 0.285,Multiple linear regression analysis showed that the ICU patients' intubation or not,payment method,families of ICU patients' education degree,occupation,level of uncertainty in illness and level of anxiety were influence factors of sleep disorders among the families of ICU patients,totally explained 42.8% variance sleep disorders among the families of ICU patients. Conclusion Clinical nurses should pay more attention to the sleep disorders among the families of ICU patients,reduce level of uncertainty in illness and level of anxiety may promote the level of sleep disorders among the families of ICU patients.