Abstract: Objective To explore the centralized skills training and assessment methods for the first year standardized training of general practitioners based on the need of the trainers. Methods Total 99 first year clinical medical staffs who received standardized training in a Tianjin physician training medical practice skills training center were enrolled into this study.According to the general practitioners standardized training detailed requirements,combined with professional characteristics of general practitioners,through the questionnaire survey analysis,we determined the clinical skills of general practitioners simulation training and intensive knowledge demands,and assessed the training effect.All trainees were examined by the theory and clinical skills before and after the training so that to evaluate of the teaching effect. Results Among 99 subjects,the main purpose of them were to better qualify for the job(68/99),finish the standardized learning(58/99) and improve clinical skills(58/99);The main needed knowledge and skills were clinical operation skill(95/99) and clinical diagnosis ability (88/99);They enjoyed the training model combined the video,lecture and operation(68/99);The favorite course of the humanities was the doctor-patient communication accounting(51/99).After the training,their clinical operation skills and comprehensive evaluation were improved significantly(P<0.001). Conclusion The standardized training that based on the demand oriented standard training courses combined with scientific evaluation system can significantly improve the efficiency of basic clinical skills and relevant theory of training for general practitioners.