Abstract: Objective To compare the effectiveness of routine care and extended care on intravesical chemotherapy,and discuss the advantage of extended care for patients with intravesical chemotherapy. Methods The patients with bladder cancer undergoing postoperative intravesical chemotherapy in the Second Affiliated Hospital of Zhejiang Chinese Medical University between January,2009 and June,2012 were enrolled into this study.A total of 104 patients in the control group received the routine care,while 110 patients in the extended care group received routine care combined with extended care.The SF-36 scores,satisfaction and compliance situation before and after nursing intervention were compared between the two groups. Results Before the intervention,there was no significant difference in the bodily pain,role physical functioning,physical health,general health,social functioning,mental health,mental,emotional role functioning and healthy conversion rates between the extended care group and control group(P>0.05).After the intervention,the bodily pain,role physical functioning,physical health,general health,social functioning,mental health,mental,emotional role functioning and healthy conversion rates in the extended care group were all higher than those in the control group(P<0.05).In the extended care group,the bodily pain,role physical functioning,physical health,general health,social functioning,mental health,mental,emotional role functioning and healthy conversion rates increased obviously after the intervention(P<0.05).The satisfaction scores of the extended care group was higher than that of the control group(P<0.05).The compliance of the extended care group was better than that of the control group(P<0.05). Conclusion The extended care can improve the quality of life,satisfaction and compliance of patient undergoing intravesical chemotherapy.