Abstract: Objective To investigate the effect and application of transcultural theoretical on health education in execution list.To improve the effects of health education and the satisfication of nursing work. Methods Three hundred inpatients in a hospital and were selected and divided into intervention group and control group randomly,there were 150 patients each group.Both groups received conventional health education.Intervention group received the health education in a traditional way which were expressed in verbal form,while,control group do a multicultural assessment on the patient first,and then carry out health education and evaluation in a timely manner according to the theory of transcultural-theoretical-basedhealth education in execution list.An evaluation of the patients'degree of health education with verbal form was made according to the law consulting content.Statistical data processing was based on the chi-square paired sample T test and rank and inspection level data for analysis.The satisfaction with nurses'service was compared by using questionnaire survey and verbal form. Results Accorrding to two groups of patients to know the situation of health education content,the number of people in two groups who could answer correctly was different.The number of control group was higher than intervention group's.The difference was statistically significant (P<0.05).Satisfaction survey of two groups,according to the number of the intervention group and control group patients are overall satisfied with 146 cases and 126 cases respectively,z=-7.044,P<0.001,were highly significant difference. Conclusion By using the theory of multicultural design health education implementation of single health education,the health education can not only improve the nurse's execution,and in the implementation of the health education,nurses use is consistent with the patient cultural background of multi-culture nursing,it let patients feel respected and make education more personalized,more press close to the patient's physical and mental needs.And it improves the degree of patients on health education knowledge and the satisfaction of nursing job.On this basis,it brings nurses'objective initiative into full play.