Abstract: Objective To explore the Effect of diet nursing instruction on nutritional index and functional recovery of patients with frontal lobe glioma,and to provide positive guidance for postoperative recovery. Methods Ninety-six patients accepting surgical treatment of frontal glioma in our hospital from January,2012 to January,2015 were selected,and randomly divided into the experimental group and the control group,with 48 cases in each group.The control group accepted basic nursing after frontal gliomas surgery,while the test group accepted special diet nursing guidance,comparing respectively in diet before and after three months'intervention between the two groups the nutritional indexes including the difference of body mass index (BMI),red blood cells and hemoglobin count,plus functional rehabilitation differences between the two groups. Results The test group had statistical significance before and after the intervention in hemoglobin,red blood cells,and BMI (P<0.05),Test group of patients with hemoglobin,red The cell and BMI indexes were (138.63±14.26) g/L,(3.52±0.34)×10¹²/kg and (25.86±4.17) L/m²,control group patients The hemoglobin,red blood cell and BMI indexes were divided into 3 months after the intervention of diet nursing intervention.Don't be (120.53±14.39) g/L,(3.19±0.18)×10¹²/L and (18.72±4.22) m²/kg,and there was significant difference between two groups in hemoglobin,red blood cells,and BMI after three months of intervention (P<0.05);the functional rehabilitation results show that there was statistical difference between the two groups in the degree of rehabilitation (P<0.05) with 37 excellent cases,4 good cases,6 general cases,1 invalid case in the experimental group and 21 excellent cases,9 good cases,10 general cases,8 invalid cases in the control group.The excellent rate of experimental group was85.4%,and the control group 62.5%,with a statistical difference (P<0.05). Conclusion Diet nursing guidance program is conducive to the improvement of the nutritional index of patients with frontal gliomas including hemoglobin,red blood cell count,and BMI,meanwhile,it is beneficial to the rehabilitation of patients'physical function.