Abstract: Objective Investigating the clinical characteristics of children immune thrombocytopenic purpura and analyzing relevant factors that cause immune thrombocytopenic purpura,in order to provide reference for predicting to the result of ITP. Methods Select cllildren with ITP who were hospitalized in the Second Affiliated Hospital of Wenzhou Medical University from October,2015 to January,2005,and conduct retrospective analyses for 1 150 cases meeting the inclusion criteria for patient.Collect basic information、clinical features,laboratory test results and other data to conduct univariate and multivariate analyses.To make statistical analysis according gender,age,initial platelet count,drug use,curative effect and so on. Results A total of 1 150 cases include 712 cases of male and 438 cases of female.The result between sex and prognosis of ITP was χ²=1.719,P>0.05,age groups were divided into 1 year,1 to 7 years,more than 7 years.The result between age and prognosis of ITP was χ²=2.970,P>0.05,the initial value of platelet,glucocorticoid and immunoglobulin were significant difference (P<0.05) in the prognosis of patients.According to the multivariate logistic regression analysis,the effect factors in the prognosis of the role of are initial value of platelet,corticosteroids and gamma globulin.P=0.000,0.042,0.049 respectively. Conclusion Initial platelet numerical,glucocorticoid hormone and immune globulin protein have positive significance in predicting in immune thrombocytopenia.The Initial platelet value can be used as an independent risk factor for prognosis.When necessary to give early glucocorticoid and gamma globulin therapy has a positive impact on children's immune thrombocytopenic purpura prognosis.This has a positive significance for the future clinical work.